ID A0A267DYN5_9PLAT Unreviewed; 703 AA.
AC A0A267DYN5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 6 {ECO:0000256|ARBA:ARBA00020973, ECO:0000256|RuleBase:RU365075};
DE Short=COG complex subunit 6 {ECO:0000256|RuleBase:RU365075};
DE AltName: Full=Component of oligomeric Golgi complex 6 {ECO:0000256|ARBA:ARBA00031348, ECO:0000256|RuleBase:RU365075};
GN ORFNames=BOX15_Mlig025721g1 {ECO:0000313|EMBL:PAA54420.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA54420.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA54420.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA54420.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA54420.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for normal Golgi function.
CC {ECO:0000256|ARBA:ARBA00003627, ECO:0000256|RuleBase:RU365075}.
CC -!- SUBUNIT: Component of the conserved oligomeric Golgi complex which is
CC composed of eight different subunits and is required for normal Golgi
CC morphology and localization. {ECO:0000256|ARBA:ARBA00011166}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004395, ECO:0000256|RuleBase:RU365075};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004395,
CC ECO:0000256|RuleBase:RU365075}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the COG6 family. {ECO:0000256|ARBA:ARBA00011023,
CC ECO:0000256|RuleBase:RU365075}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA54420.1}.
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DR EMBL; NIVC01002911; PAA54420.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267DYN5; -.
DR STRING; 282301.A0A267DYN5; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017119; C:Golgi transport complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR010490; COG6.
DR InterPro; IPR048369; COG6_C.
DR InterPro; IPR048368; COG6_N.
DR PANTHER; PTHR21506; COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6; 1.
DR PANTHER; PTHR21506:SF0; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6; 1.
DR Pfam; PF20653; COG6_C; 1.
DR Pfam; PF06419; COG6_N; 1.
DR SMART; SM01087; COG6; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW ECO:0000256|RuleBase:RU365075};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365075};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU365075};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365075}.
FT DOMAIN 44..155
FT /note="Conserved oligomeric complex COG6 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06419"
FT DOMAIN 187..702
FT /note="Conserved Oligomeric Golgi complex subunit 6 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF20653"
FT REGION 334..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 703 AA; 78183 MW; 3F5961F912650A61 CRC64;
MPIESQSSHT TAESEPPLIR KLKKVLDTRL ENDLELVESL KAVSEFFTEN NIRSRRSLRS
DMESRYVVIY EEFLHSFKSV KDDLEELYDA VSAMNSSCKD MSVRLQEAKS QTEHLLRETS
RIQRESEEYE IRSRVAEVVL ELFQLTPEQE QQLTDKASPV TEDFFKALER SKQIHSDCKL
LLMAQNQRAG LEVMEQMSVL MECGCEKLYR WIQNECRMQA GESAEVTALM TQAFQVLQDR
PVLFKYALDE YANARRAALV KAFIEALTRG GSGGGGPRPM ELHSHDPQRY VGDMLAWLHQ
ATASETESLD SLLKLCDDDA EADGNEAAVA IGNEAKEEDG EAEAGAANGT DNSTDIASSR
SSRRQLRAAC LCSLSEGVCR PLRLRVEQAL VGVQDASVLY RLHNLLRFHQ GTLDRVLGSD
SSLATTVGDL GQLCWRLFFG ALTNGAQRAL ETVEPLAAYA SGTAAGAGAG IDDWDRLRAP
PAVAETLRLL QQVLTAQDSG MAPLSQRRDD LRQVLDTCID PLLKLCTVTA TRLSPLELAI
FMANSLHSLQ TGLAAYEFTE THIERLQAQL EPQLDALVAE QLSHILVSLR MLELYQTVEQ
HQQQQPQQPL SYLEAPCLSL SAVKAAAARF NSYLANPDSL ALPQLQALQS SKLRQLVTRR
VADQIHSVYT AIYDAIVKPE NLFGKEFATV LVRNPDQVAK LIL
//
