ID A0A267DZT8_9PLAT Unreviewed; 1912 AA.
AC A0A267DZT8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=PLAT domain-containing protein {ECO:0000259|PROSITE:PS50095};
GN ORFNames=BOX15_Mlig015709g1 {ECO:0000313|EMBL:PAA54099.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA54099.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA54099.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA54099.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA54099.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA54099.1}.
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DR EMBL; NIVC01002969; PAA54099.1; -; Genomic_DNA.
DR STRING; 282301.A0A267DZT8; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 2.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 13.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR22906:SF43; COMPLEMENT FACTOR PROPERDIN-RELATED; 1.
DR PANTHER; PTHR22906; PROPERDIN; 1.
DR Pfam; PF01477; PLAT; 1.
DR Pfam; PF00090; TSP_1; 13.
DR PRINTS; PR01705; TSP1REPEAT.
DR SMART; SM00308; LH2; 1.
DR SMART; SM00209; TSP1; 13.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 2.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 13.
DR PROSITE; PS50095; PLAT; 2.
DR PROSITE; PS50092; TSP1; 13.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1912
FT /note="PLAT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012040421"
FT TRANSMEM 1315..1336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1522..1540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1560..1586
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1614..1636
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1656..1675
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1733..1751
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..145
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1360..1477
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
SQ SEQUENCE 1912 AA; 207740 MW; B0F8244D4D6433B7 CRC64;
MLRILLLLLP LLLLQQLLGV SGQAQEESYT LVIKTGKTGT TNKVFFSLKG QMGDSPQQSI
NFDGSDKPIT SMFTPGKVDV IEGKFRGALG YISTVKVSQD SYNGWEIESI VVFSDTTRVS
NNETYIVRQP QDISFNVNCG WSAWSSWMTC QGTCATGGVQ MRIRNPNSPP RINSGKACEG
SEFEQQPCKL AMDCPVNGNW SDWSPWSTCS VSCAQGSRSR SRTCTNPAPA NGGLDCVGAA
SDTGVCTESP CPIDGQWGSW SPFSACNASC GPGVQTRARL CNSPEPKFNG RNCQGDGIEL
KTCELTPCPI DGGWSSWGEF SSCSSSCGDG IEIRNRPCTN PPPQFGGRPC PGSANDSRSC
NLRPCPIDGQ WSEWSTFSGC SRSCGSGKQW RGRQCASPVP QFGGLDCPGG ANETRECNTN
PCPVDGGWSA WSAFADCSVT CGNGSHSRQR SCSSPEPQFG GLNCSGKAVE FGNCNPRPCP
IDGAWTSWSD YSACSLTCGR GRQWSQRSCS APEPQFGGKN CPGNSTRDRA CLVTECPVDG
LWGSWGAWES CSVTCGSGTA WRRRHCDSPE PQFGGSRCSG AGNESTPCHP EDCPINGGWS
PWSEFTACSR SCGGGQRSRT RRCDSPPPHA GGADCVGSGS DVQDCGTDPC PVNGGWAQWS
AWGSCSRSCG SGLVQRSRGC TNPVPEFGGD DCAGEAVQST ACDIPACPVN GGWGAWGQWG
DCSLSCGGGN QLRSRQCDSP RPQNGGGACV GTASDGRQCN TDPCPIDGGW SAWSEWSGCS
TSCGTGKSTR QRGCSSPVPQ FGGRGCSGSG SDIRDCQQGP CPVHGGWSEW TEFSNCSVTC
GNGTRSRSRS CSSPAPQYGG RFCLPCTANL TYPESADNAS VSLATVVKDY VSVEDNCSYK
GNYYEVDGDL IIWDDDVQYA NCSMEPCIST LADKANSFVD EFLKGLNNSG TNKSDSESMK
AAQEMVNKIT NLLADQLKNA EVGKPVMIDA KGVSVGVSKV NSSNMAGSEM KSGDKGGIVL
GDAEDTGVDG QDASLKFSAL DPKTFFPGAD KKDQSAAVVS LNLAQGTEVV KPSNASKVSL
TLSLPNQNQE TTENLLQPVA MKRGKRMVQK FTFEAANTAI KASLELPSSD SYLMMFRGGV
PANFSKQANF TAWVHSNETM KIETDGSLEV RLKFDTALAA ARRRRRRETA SPEKPLTLSV
FIPGGQMAAG SAVFMSLELA DNGTAAAASG SNVTTESANM SLTVGVASIT PRAWSDLLGG
WVDTDAEVAE ESSIEKMVFK SNFFGSYSGK MFIAPNTINF ATVFNNFAGK LAENFVTLLV
LCLIIGIYVV VSVWMWRLDR QEAANLRYEP LEDNEFDNDY TFIISVYTGD ESGADTTSNV
FINLAGTWGS SGPSQLSDGV RQNFSRGSVC NFAMTTRAPL GELRGLKVWH DNSGKKPGWF
LEKILIEDLQ TKKNYVFMCD QWLAENKFDS RTMRVLPEVK QDQRFQEMML RYKAGGVVNK
HVITALFRKT GQSNYSRLQR TGVANAMFFL TMVCNAMWYG KGDDLDAEAN FSIDLGPISV
TWFQLYSGIL SMAITYPCIF AAAEIFRRTK KWQRRWSEDD VESKKKEIRL PKGFLVIGWG
LLLLGVGLSF FFTFLYSIEW GKEKANGWLK SFFLGILQLV VVTDPICLLI VFVVAKKIFG
QKESEENVFE LDDLINDDLK QVLDGTEYAP PDPTRMEEIR AERRNNQKMS QTFTDVMSYV
VYMFLLVALA YDSRDQVSFR QNQNLKDQFL TAAPTRFNDF KHVFDWLNGS IVPRLYRTTE
YNGEPLTGDL KDAIDTCDCI KQGPFRLRQL RVNPRKCPVT WPFKAYPRNR GSAHRTSLPK
RRTRRFTVRC GCPTATAGCG MRHCKCGQSR RSSECGRMKS FYKPFGTVAL TP
//
