ID   A0A267E0M8_9PLAT        Unreviewed;       637 AA.
AC   A0A267E0M8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=Coiled-coil domain-containing protein 22 homolog {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=BOX15_Mlig022335g1 {ECO:0000313|EMBL:PAA55098.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA55098.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA55098.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA55098.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA55098.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the CCDC22 family.
CC       {ECO:0000256|ARBA:ARBA00006438}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA55098.1}.
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DR   EMBL; NIVC01002811; PAA55098.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267E0M8; -.
DR   STRING; 282301.A0A267E0M8; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   InterPro; IPR008530; CCDC22.
DR   InterPro; IPR048348; CCDC22_CC.
DR   InterPro; IPR048349; CCDC22_N.
DR   PANTHER; PTHR15668:SF4; COILED-COIL DOMAIN-CONTAINING PROTEIN 22; 1.
DR   PANTHER; PTHR15668; JM1 PROTEIN; 1.
DR   Pfam; PF05667; CCDC22_CC; 1.
DR   Pfam; PF21674; CCDC22_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT   DOMAIN          7..113
FT                   /note="CCDC22 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21674"
FT   DOMAIN          309..601
FT                   /note="CCDC22 coiled-coil"
FT                   /evidence="ECO:0000259|Pfam:PF05667"
FT   REGION          281..333
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          602..636
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        303..333
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:PAA55098.1"
SQ   SEQUENCE   637 AA;  69572 MW;  14E1E8E811A21A1E CRC64;
     QLASHPMEEV DRNVIRQLVS IGCDWDPKVT SIGQLTAEMM VEAVGRCLRL MQPDESFSIT
     LPDGMNIRYR IGQQLAEAVR GLGYRGELGY QSLLYPSERD ARSLLVFLVE RLPKDEAGEL
     KDALTGASGQ QLLDRLIAAR CRAQLAAPWL PACCRPDGFA LRQGGLCFEG GGGGPCEFRT
     VYPCVPNRAA PAAAGSEIPP SVRQFQRGLP FFCGPAGRPG CWAASAAPGP SLLSWTASLL
     LAERREEEAA IGARPSTADT ESGGVGIDVE LLPRSLRQAV ADAVKQAAGG RRPPPPPKPP
     KPTRKKSAND EHQQLLKSAE TEATESAEAR AARAREDLER LRAELEAVAK ATGKAERRAA
     KLDAQTAEAQ AAADAWEQRE RQEAQTRLRA AELLAAGEAD RLEEAQAAQE SKLARQSEQW
     AERRAAMEAE RRALQAELDA RSSVLAGRLD ELRESRADLA ACREDLRARE AERELLQRAA
     DRLARRLAEG DPSLTRRREL TRGLLDFAAN LKKQRAELGR ISDELRAAQK EINRLTGKLD
     RTYRVADEAV FSGASDPTGK RLYKLLAGLH QHCDAVLRCE EDKSTLQKET IDLEDHILVE
     RRRRMEENAD KLAADLAELK RANKALKAAA AAAAASG
//