ID A0A267E0X4_9PLAT Unreviewed; 1733 AA.
AC A0A267E0X4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
DE Flags: Fragment;
GN ORFNames=BOX15_Mlig013021g3 {ECO:0000313|EMBL:PAA55198.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA55198.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA55198.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA55198.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA55198.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA55198.1}.
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DR EMBL; NIVC01002790; PAA55198.1; -; Genomic_DNA.
DR STRING; 282301.A0A267E0X4; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF36; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 5 ISOFORM X1; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 80..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 918..938
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1119..1144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1165..1189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1195..1214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1234..1253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1259..1280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1312..1333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 526..766
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1387..1620
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PAA55198.1"
SQ SEQUENCE 1733 AA; 195386 MW; 089A5F7DC39B65F7 CRC64;
TRHLQRSRHI YSAPTCKLNF RFKPTNTNTK LRRVDGLEAQ FNQTFLPSDV RIYRLKMAIG
TLEQTNQLLM LMLHMKRWKF IWFIIVFLSA ISNHMLFPII DGWMGTLGQV YTSIDTKRFV
ESNLILAETY KYERQLESLK SILDSENVRD SGSLIETCSS PKACKARMFS VMFGRVDTSK
FSNFVTYNYS NRPRVECQMS YGGDLNCPYL GNLAVMSSYP NKWKNYMYKE IHFFSLTSRK
EGKKTDSVRG NTTKCAKHEN FETVFSRTVM MQCVIIIGSM SFYFLVSTQS CIAQLKRDGF
LQLMMQKGLS VSAYWLVISA MTAIEIVSFS IIFVTSLAVQ CPGFFNPVHM LLVFLMSLFY
MVALTSVGLL LTVTFGNYYY VGLMTVLIAI ISMVLVLVNR MAISTIVVLK IILLFIFPLG
HFAEFVQGIL LSEIRMESIS IYNISILVVT LLSAVVLVLS TLVLDYVSGS GNGFRLPAQF
FIRREFWTAQ PASKELGPEK DDPLYGEEPP EYANIEPVTD GLRPLVRMSH LSKAFQARKA
CGKSETFYAV KDMSAMVYEN HITAIIGHNG AGKTTLLNLL TGADTPTTGH ASICGIVGTN
PLKRLRLRGH LGICPQIMNF ASSITVEQTL QLLVISCGLQ WNECQEELTR MLKVARLDNK
RHYRTGRLSA GQQRKLAVIM ALMGNPRVLF LDEPTSGLDP ESRRRMWRLL QEYRHGRAIL
ISTQFMDEAD TLADRKIFIS SGALLCAGSS LFLKSAFDCG FVFEVTLKNE KHSKLVKKQI
LEEFKMVKVK KSFGVNLNFQ LPARDINFLP ALAQAFEKRM TLVSAFGLLQ ASLYDIFMKL
KDLDPEAVQE MFSEDKENAE GFEDEQEETF SEASTDRNTK LSCIVTREHA PLAPSLLRQL
KAMIIVNVMR LVRTRMRLAC RVIVPAILLI VLIITAAIER SNNNHRIHLR NNMTNEGEII
KHGVCVFEKV EGKPRMLWEV DKRRCSWLYA GKTAPMEIAK NYLALQKPKE VELQNFLREK
SNIEKIQKVC KSRKPDAEPC PITYTIDWGD NTPNSERVIY YGTYDIYENF NSSKSASLTI
GTYMRATSYF TTVARSDEPP DDKKFLFSAE SVYDFRTTFV PAFGAFFQIL IMSLIPATFL
DDIIEDKETQ VRYQLSTIGM SNFSYWLTNF IIHWVQYATV YSLSTLLLLS IVQTGYSSSF
FMTGVFLPIL LLGLPSNQLM TYVLSTILDR ANHLVTIMYL FTSILLAFIV LLVQLNNVAS
IILISVLPPF APIALTFYGV KTIFYSLSYY NKDSISDITE LKGSLFFSQP HVVAAFIAII
LHFAVLLTAL AIIENKIILL QLLEARLQIK CTSELPVGTF DNLTEDPGVK EETERIDANP
NSEMNLLEVS HLAKTYPNGT KVVRDISFAT GPAEIFGILG PNGAGKTTAL STIVGRLNAT
RGRCEVRRQD EWLPSGLATS RGAIGYCPQS DPLYGCITAM EHLKFYANII GVPDSKLDSL
IEELADSLDL NLDRESLAEH LSVGIRRRLS LAISLLSEPS VLVIDEATTG VDPEGKRFLW
QAIRAAATLT CTVLVTTHSM EEVEAICNRV TIINRGLLVG LGTVQQLKSL YGRSYSLEIL
LNTSVDEAED SVEAKMATLI EAVSKKFKDT KVVEEFHDRV HLAIPVGSVS RLSVALSWLL
ENRKSLNIYY FSLHQMSMDQ VFERMVKHHD ATIRQRTSIF SNVSHTSDNQ SLV
//
