ID A0A267E281_9PLAT Unreviewed; 610 AA.
AC A0A267E281;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 22-FEB-2023, entry version 16.
DE RecName: Full=NUC153 domain-containing protein {ECO:0000259|Pfam:PF08159};
GN ORFNames=BOX15_Mlig006702g1 {ECO:0000313|EMBL:PAA55673.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA55673.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA55673.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA55673.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA55673.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the ESF1 family.
CC {ECO:0000256|ARBA:ARBA00009087}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA55673.1}.
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DR EMBL; NIVC01002721; PAA55673.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267E281; -.
DR STRING; 282301.A0A267E281; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR InterPro; IPR039754; Esf1.
DR InterPro; IPR012580; NUC153.
DR PANTHER; PTHR12202:SF0; ESF1 HOMOLOG; 1.
DR PANTHER; PTHR12202; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 568..588
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 1..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..538
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..50
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..149
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 237..253
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 610 AA; 67531 MW; ACB61070FC52314F CRC64;
MVKKRRNAAG NRDEEWRSDP RFGHVSTDPR YRSASARKAT RVEIDDRFGA MFTDPEFSTS
VRSDKRGRPV AMSSRQDLSR FYGLKQGRHG EDEDDNDEVE ASSDNQEDEE SEDAVDKDED
EEDEEVAEEE SDSDEEDDDD DEQNEADNDE GSDSEARSSS DEEFRNLERS SSAAIDEEND
QSIVPTNRLA VTQQDWEQIK ATDLFMLLSS HCPSSVGRLL SVTVYPSKFG QRRMAEEAKA
GPLELRRKAS SDPAKKSSTS SGSYRRSLRR YQLKRLWYYY AVAEFDCTPA AASVYEQCSG
LEVESTGGCL RLSYVPAGME FGGPDDVPDE WRHLVTRCTG LDPAAYKPRK LTAGLLNRTK
VGLTWDETPT ERTRYLQGLF NKTDFNEDDP DLNRLSEFLN LSSDESDNDE EDSDAIKART
AKLRRALLGD DVGADKAEDN ADNGSELPAA FSDDELPDDI ALALQDVDAK AKSSAKGQKQ
QEQSEPKESR KRTRRRRLKE QAKRAKLAKA GLLPSKADGA GGSGDSDEGD SGEGEGVMPA
SEQELAMLVA DRVAGAHSTV TAADVAADER FGALFTDPNY HVDPTHSEAS KAVEVQKLIV
GAKRKRAAFD
//
