ID   A0A267E663_9PLAT        Unreviewed;       803 AA.
AC   A0A267E663;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=BTB domain-containing protein {ECO:0000259|PROSITE:PS50097};
DE   Flags: Fragment;
GN   ORFNames=BOX15_Mlig000336g3 {ECO:0000313|EMBL:PAA57073.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA57073.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA57073.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA57073.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA57073.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA57073.1}.
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DR   EMBL; NIVC01002536; PAA57073.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267E663; -.
DR   STRING; 282301.A0A267E663; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR24412:SF35; ACTIN-BINDING PROTEIN IPP; 1.
DR   PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 3.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 4.
DR   SUPFAM; SSF117281; Kelch motif; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          59..124
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          443..471
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:PAA57073.1"
SQ   SEQUENCE   803 AA;  83318 MW;  03FCBA88C0DA4CD7 CRC64;
     KQSAPMSLSP EVAPMPVNGS SDGYGSDSDT GSSDLLLDNC QLPEHFVRLS KLRQEGVFCN
     VQVSVSGRDF LAHRCILGAA SPYFLRLLLA DPNCGHFALP RGYSPDAFAL LLEFSYTGRL
     MVPDRLLPQV CSLASLLAMR PVLDVCSGRL LQTCLLPRTA LELRAQLTDC QPVLDSIDAY
     IAANLAEVLS FGAACLPKIM LDLLVCGIGG VGLNQLCDLL ADWLARSVHD ASTSVADAAA
     SASAAVAAKA SSSPRGTSMD TPGRPGDSSR CDAMVDLDCL ERMSSQSHLL YLTPGNVLID
     CDDLASTNSL GSAPDRDLAK SVPQIRDYID SKRLQARVLS SRHRGPSPLS RSVLGVLAPP
     SCNADSGSVD SAVDSDASSS DQAAATQCLV RVGSTLALLS VRLLPVLPPE DAAGGLGGGF
     QRQLSVQSSS GGCVSAGYQR QMSGQSSAGG VGVGASSESD TGGDTAINGS PPSVSPLLAA
     PALGDSGVAL AAMSTPRSAF GFVGFNDGDS GENFYLLACG GYNRGQCLSS AEILRPGWGG
     GCWTPAPPLL TARSRCSAAV LCVGSDSRVY VCGGSDGNCE LSTVEIFDGN QWLAGPPMQQ
     ARSGCCAVAM DGVLYCLGGR YGADSLRQAE MLDPRVGRWQ PLPPMLAWRN ECAAAASNGQ
     LWVAGGADNW GGQCLASVEV YEPRADRWIR APRQLSQPRR GAAMSELAGR LWLVGGSDGQ
     RPALVACEPV PVMPLGDETP TMSTVETSEL ATPALQLAMP RANLGLAALP ASISAGFGRP
     PCLLAVGGFS GKVFLDCCEL LHL
//