ID A0A267E9L5_9PLAT Unreviewed; 710 AA.
AC A0A267E9L5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 13-SEP-2023, entry version 18.
DE RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};
GN ORFNames=BOX15_Mlig019750g1 {ECO:0000313|EMBL:PAA57594.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA57594.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA57594.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA57594.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA57594.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362056};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362056}.
CC -!- SIMILARITY: Belongs to the organo anion transporter (TC 2.A.60) family.
CC {ECO:0000256|RuleBase:RU362056}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362056}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA57594.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NIVC01002469; PAA57594.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267E9L5; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004156; OATP.
DR NCBIfam; TIGR00805; oat; 1.
DR PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR PANTHER; PTHR11388:SF76; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER; 1.
DR Pfam; PF03137; OATP; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU362056};
KW Membrane {ECO:0000256|RuleBase:RU362056};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Transmembrane {ECO:0000256|RuleBase:RU362056};
KW Transmembrane helix {ECO:0000256|RuleBase:RU362056};
KW Transport {ECO:0000256|RuleBase:RU362056}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 47..66
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 78..96
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 146..173
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 225..249
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 367..390
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 405..426
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 438..459
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 563..588
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 600..621
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT REGION 258..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 680..710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..286
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..306
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..710
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 710 AA; 73666 MW; 51D697DAC232F1D3 CRC64;
MPCNINAYTL CLGLFALVYG SFDTYLISML TTLEKRFNLP SKLSGLLQGS SDFGYLLGVL
PVSFYGRQAH RPRTMGGLGL LLSLGILIMS SPYYFFGPMP AGAGGSAASQ SSSPSAGLLC
NSTATTSAAA AAVAADGQQP LSRQSAVAYF VLVLGAFLVG VGSTPFWNLG LAYIDDHVSK
VRAPVYISAM MALRFVAPVP GYIIGGQLAM LPESLLSGAA EHTGVGAWWL GFVCLSGLTA
CCSLTMFCFP RQLPRPDDGQ PEEIELPTEK RLPPASDLDE PDGRALCEDG SAAPQEQQQN
HQAADCDASK SGLPTPAKAA EAAAPGAENG DRPTPAVDLL NSVVSLDPAS LVKTGLSHTL
RRLAGNLTFL ALLIGAALEF LAFMGFLAFL PKYYQVGFGV TTGEAGLYAG IVEGFSSALG
TLGGGIFMNR ARLSLSKLLA LTTGVCLAIG LLGNIGALLE CRATPEFTDF DSPAACALCD
CDSRQYRPVC SGNASYLSPC LAGCSSFSFY NSTESPQPLP LLASFEGCGC DAVASSSSTA
SPAGFVAFDG FCGVGGGCSA ALIAYNCIFF CLNLLAGAVK SIVCVIVIRA ISARDKDIGF
GFITFAASFS STISPILYGA MIDAFCLHRD AASGGVFARC LLYNIAGIRI SQHLLRSVLR
ILCGLAFVVA TVGARSNPHI QRNEREIKRQ QRGGGGGSSN GASAAPQEAG
//
