ID A0A267EB09_9PLAT Unreviewed; 1073 AA.
AC A0A267EB09;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=TOG domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BOX15_Mlig020622g2 {ECO:0000313|EMBL:PAA57989.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA57989.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA57989.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA57989.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA57989.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA57989.1}.
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DR EMBL; NIVC01002426; PAA57989.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267EB09; -.
DR STRING; 282301.A0A267EB09; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR040122; Importin_beta.
DR InterPro; IPR041653; Importin_rep_4.
DR InterPro; IPR041389; Importin_rep_6.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF5; IMPORTIN-5 ISOFORM X1; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF18808; Importin_rep_4; 1.
DR Pfam; PF18829; Importin_rep_6; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT COILED 826..853
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1073 AA; 118723 MW; 46B39DBC892794BF CRC64;
MVEHGDFASN SLNNHQSDFC TLLNGLQSMH NEERTNAETQ YEQIPAQTRL GLLLQSMSTG
QTTELRSFSA VLLRRLLVKN LDEAYEQLNP TDQASVRQQL LLCVTNEPDA SVRRKAADAA
AEMARNIGDV AASGNDSSNA CGWPEFVQLA AQCVHSGQPA TQQIGLHLLA QVPSAFSHPA
SLPLVHQLLD KAVSDAGSAA VRSAGVKAAC AFLVANEEEE GTLNQMRDLL PPMLRGLAES
IVTPESDDAS GDEDAVLKGF VELAEVLHKW LRPQLTQLIE LCVQTVGNQQ LPDSRRHLAL
ELVVTLSENA AASVRKAGAG KVGALVQQVL MLMTDLEDDP EWALQENKDE DDDDESNAIN
GETALDRLCC GLGGKAMLPH ILELVPHMLR SPTWQHRHAA LMAVSACGEG CHAQMESMLD
NVLAAVLPFF QDPHPRVRYA CCNAVGQMCT DFGKIMPKKF HAQIVPNLLR LFDDYANPRV
QVHACAAMVN FSESCPKSIL TIYLDSLISK LEQILSTKFQ ELVQKGNKMV IEQVVTTLAS
VADTAEEKFI QYYDKFMPCL KYIMENAVQK ELSLLRGKTI ECISLIGLAV GKEKFLADAS
AVMQMLLRTQ TDHPLAEDDP QMTYMISAWA RMCKIMGREF EPYLPLVMGP VMKAAEIKPE
VCIMDSEEVQ NAEQDPEWQF IKLADEQNFA IKTSGLEDKA NACQMLVCYA RELREAFAPY
TEQVAQLMVP LLKFYFHDEV RSAACESLPH LLECARSQGP TFLGNLWGYI RPSLIAAIGD
EPEPEVQADG LSSLAQCIEA MGAGCLADSM DPCLELLEKL LNSHFEKAEK RQAARQDEDY
DDVEEERLKT EGEDDEYVLS RVADVLHSLL SAYKQQFEPQ LQRLLPLIAK LLDESRSWLD
WQWGVCIFDD VIEHLGPASF RYQEVFLPRL VSSAVHKEPD LRQAALYGLG VAAQFGGPQY
HPTLSQMMPF LVQLIAAPDS RNEDNVSCTE NAIAAATKIL KHCPAEVAGQ PPEQILPMWL
SWLPVSEDRE ETEHVYGFLC DLIEGNDPNI LGPNNQNVPA FWPSLASACT ARP
//
