ID   A0A267EJG0_9PLAT        Unreviewed;       307 AA.
AC   A0A267EJG0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Tetraspanin {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BOX15_Mlig032479g2 {ECO:0000313|EMBL:PAA61663.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA61663.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA61663.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA61663.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA61663.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC       {ECO:0000256|ARBA:ARBA00006840}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA61663.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NIVC01002008; PAA61663.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267EJG0; -.
DR   STRING; 282301.A0A267EJG0; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR000301; Tetraspanin_animals.
DR   PANTHER; PTHR19282:SF556; IP01956P; 1.
DR   PANTHER; PTHR19282; TETRASPANIN; 1.
DR   Pfam; PF00335; Tetraspanin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 1.
DR   PRINTS; PR00259; TMFOUR.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        72..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        103..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        273..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   307 AA;  33179 MW;  0227D878F2436530 CRC64;
     MGCSTSLAKM ILFIFNVAFF IFGIASLGLG IWVAVNKNDL FRFINLVDSQ VTEGANQGDI
     SSVANQSGAV TAAGYVLIGL GLFTLLVGFC GCCGAMKESK CLLMIYAGLV GLVLVLEITA
     AIMAAVFQSH VRNSAEAGML RVQNRFFVAM PDYLRVQGTN GANALATFLI NYVQLMFECC
     GARTIGDIAN SSSWTASNRT FAGKELKVPL TCCRLRENRK NDVMDPRYNW TNFADDLQDS
     GCPYKPLGGN GGLNNATCYN SLLEYVSQYS KPIIIICVAI GLFEILGILF ACCLIKAIEN
     DVSYAKQ
//