ID A0A267EJQ6_9PLAT Unreviewed; 367 AA.
AC A0A267EJQ6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=OBG-type G domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BOX15_Mlig010951g1 {ECO:0000313|EMBL:PAA80815.1},
GN BOX15_Mlig033011g1 {ECO:0000313|EMBL:PAA61755.1}, BOX15_Mlig033011g2
GN {ECO:0000313|EMBL:PAA61664.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA61755.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA61755.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA61755.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA61755.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA61755.1}.
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DR EMBL; NIVC01002008; PAA61664.1; -; Genomic_DNA.
DR EMBL; NIVC01001999; PAA61755.1; -; Genomic_DNA.
DR EMBL; NIVC01000566; PAA80815.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267EJQ6; -.
DR STRING; 282301.A0A267EJQ6; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01896; DRG; 1.
DR CDD; cd17230; TGS_DRG1; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 6.10.140.1070; -; 2.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR045001; DRG.
DR InterPro; IPR031167; G_OBG.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR031662; GTP-binding_2.
DR InterPro; IPR006074; GTP1-OBG_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR004095; TGS.
DR InterPro; IPR012676; TGS-like.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43127:SF1; DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR43127; DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR Pfam; PF16897; MMR_HSR1_Xtn; 1.
DR Pfam; PF02824; TGS; 1.
DR PRINTS; PR00326; GTP1OBG.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF81271; TGS-like; 1.
DR PROSITE; PS51710; G_OBG; 1.
DR PROSITE; PS00905; GTP1_OBG; 1.
DR PROSITE; PS51880; TGS; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 64..289
FT /note="OBG-type G"
FT /evidence="ECO:0000259|PROSITE:PS51710"
FT DOMAIN 289..365
FT /note="TGS"
FT /evidence="ECO:0000259|PROSITE:PS51880"
SQ SEQUENCE 367 AA; 40738 MW; 7D411F5250FC7EED CRC64;
MSVVQKIAEI EAEMARTQRN KATMGHLGLL KARLAKLKRE LIEPKGGGGG GTGEGFDVAK
TGDARVGFVG FPSVGKSTLL SNLAGVYSEV AAYEFTTLTT VPGVIKYKGA KIQLLDLPGI
IEGAKDGKGR GKQVIAVART CSLILIVLDV LKPLQHKRLI EHEVEGFGIR LNKQPPNIGF
KRKDKGGINL QCLVPQSELD GDVVKGILNE YKIHNADITL RYDATAEDLI DVIEGNRVYI
PAIYVLNKID QITIEELDVI YKIPHCVPIS AHHKWNFDDL LELIWDYLHL VRIYTKPKGQ
LPDYEAPIVL KTGRQTVEDF CNKLHRSIIR EFKYALVWGS SVKHTPQKVG KDHELADEDV
VQIIKKV
//
