ID A0A267EKV9_9PLAT Unreviewed; 596 AA.
AC A0A267EKV9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=LRRCT domain-containing protein {ECO:0000259|SMART:SM00082};
DE Flags: Fragment;
GN ORFNames=BOX15_Mlig010234g1 {ECO:0000313|EMBL:PAA61412.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA61412.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA61412.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA61412.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA61412.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA61412.1}.
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DR EMBL; NIVC01002034; PAA61412.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267EKV9; -.
DR STRING; 282301.A0A267EKV9; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24369; ANTIGEN BSP, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR24369:SF210; CHAOPTIN-RELATED; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00369; LRR_TYP; 2.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 270..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 103..152
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT REGION 325..402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 483..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..344
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..515
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PAA61412.1"
SQ SEQUENCE 596 AA; 66307 MW; 2F402A0CE5EC6BDF CRC64;
SMTCNERGGI TDGIWSSLIL LPSLQKLTLE YNKLSSIPDF YFSYFRNLTY VNLGNNNISK
LTSASMYGLG ATKLLLQNNS LSYMDNCTLS MFEKLDSVSL GGNPFYCGCA MQWLWRRVSA
EIAINLVSMQ CSSPAKLAGR IWNTLSESDF CDLGETAPNN CSIQIPTTES PTTFSYLLDI
KITKDTESTV RLEANLDRLV GKFSAYFIRY WLISQPEVVF NTSLMPLKAA VTTLRARVNE
KYRYCYVLSN GTSQLLESLA NCRDFTLTGL ASAAVIAISV LAAILGIALI FVIVCLVCKK
LRHRQSTQMR GYTEEDPYAY VYPDEKQVGK QPPNQSQFQA TLRPESKRFS KRSRPNLSGS
RPSLATSTTT LATPRMSSSG FAIQNGARPM SGQSMNQQHH QNPRLLREGV QPSQSMLSIA
NDKRARPEQH TQQQLSRSQD HLSSVSERGR SSRALPPAPR QAHSQELVLD VSQAVGRFKH
LQQYPEQPPS LPPPRSRLPS LASEQQQQQP QPLSYTGYYG DGAYLPMSQA TAGCLGESST
DQDHRLQTPV SLAYNEYLSD NEAQHGFSHS DRVAGGVDNS AFQRHETSGY YEMGQF
//
