ID   A0A267EMH8_9PLAT        Unreviewed;       400 AA.
AC   A0A267EMH8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 11.
DE   RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
DE   Flags: Fragment;
GN   ORFNames=BOX15_Mlig009631g2 {ECO:0000313|EMBL:PAA62039.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA62039.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA62039.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA62039.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA62039.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA62039.1}.
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DR   EMBL; NIVC01001979; PAA62039.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267EMH8; -.
DR   STRING; 282301.A0A267EMH8; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR11695; ALCOHOL DEHYDROGENASE RELATED; 1.
DR   PANTHER; PTHR11695:SF294; RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT   DOMAIN          32..396
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:PAA62039.1"
SQ   SEQUENCE   400 AA;  41697 MW;  B090E019853DF6AC CRC64;
     LRHAAVQQLS TAPAPSAMAS HSMRSVNSYE YGGLEKLQLT DTMKVPVLRQ PDDILVRVHC
     STVQPIDIAL LSGYGSVLLP LAARAAACGA EPDAVPPALP LILGRDFCGE VVAAGPDCPP
     ELRQPGRLVW GARAPFESGC HAEFALASAR HVRPVPDGVD PAAAACVPYP GLTALAAMLE
     AGLPTPASSF NWPLRCRSSR PDPAVLVLGA SGGVGLLLLQ LIRCLLPACR LVVTCPARHV
     ADLPAAVNGC QLDSVLASGG HDSAATLQQL TAAPATFDAI IDLTRDAASR RRLLPTLRPG
     GRLATVSSPL LRLFDQRGVA GGAPVAARAF ASDRAAGIRW AFFAQSGANL DYLARLLALG
     RLAPRIDRRF SMSGEFRTAF ELAAGGDGRS MGRVVLDVAS
//