ID A0A267ERI2_9PLAT Unreviewed; 737 AA.
AC A0A267ERI2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
DE Flags: Fragment;
GN ORFNames=BOX15_Mlig007225g1 {ECO:0000313|EMBL:PAA64088.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA64088.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA64088.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA64088.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA64088.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA64088.1}.
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DR EMBL; NIVC01001783; PAA64088.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267ERI2; -.
DR STRING; 282301.A0A267ERI2; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 4.
DR Gene3D; 2.10.25.10; Laminin; 9.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR24039; FIBRILLIN-RELATED; 1.
DR PANTHER; PTHR24039:SF28; FIBULIN-1; 1.
DR Pfam; PF07645; EGF_CA; 10.
DR SMART; SM00181; EGF; 9.
DR SMART; SM00179; EGF_CA; 10.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 3.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 4.
DR PROSITE; PS01187; EGF_CA; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..737
FT /note="EGF-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012967063"
FT DOMAIN 350..392
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 393..433
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 444..483
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 489..529
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PAA64088.1"
SQ SEQUENCE 737 AA; 80902 MW; D092A05513D92A69 CRC64;
RKLRLKFRVT TLTETLSQTM LQAMLLLLVA TCTVAQSTTE IGQAVDIDCL VGFEAVNGVC
TDVDECQRLN DDGSGVLEED RRDICGNYVH SHRPGYRCVN TPGSYRCERI VDCGFGYRLN
ETLGVCIDID ECAVLGYEAA CGLKLPIKVC INLEGSFRCD YRTCPPGRYL DRTTGECNPC
RRGYAKNLLD ECVDIDECGS RKDSCPPHMR CVNYIGGYEC KHKIFCPMGR RANYNGTLCI
DIDECAEHPK ICGVGRNCIN LDGSYRCESK QCGRLQELNS QSGECVCTEG FRMNATSKLC
EDINECTEGR HNCDANDVCR NTRGHYDCLS RDKVCEPGFG LSFDHSSCVD IDECRLGHHK
CSEREVCNNT HGSYVCECSP GFHRVGGSRE CTDIDECTLK NGSSPCPAHL QCRNSPGSYT
CVCPLGYQPN NASDIVNASL TCVDIDECAQ LPDICGSVGT CRNSPAGAYT CTCPGGYMAT
DVVRGTCADI DECQLNACPA GAACRNTPGN YDCQCRPGFL FVRQKNLCED INECDQPDNE
CAQNGTSCFN YRGGSACYRH SCPEGFRLPR SGSGLHTANT LSFSCRLIGE ACHPAPRFNG
GRQQRRVCIK RHRIVHKAQE MPLANRGSFV TVQSDMRLGL RECQFRATLF RASGLRTTSY
QVETTAAPTD EEAVRFHQRQ TQRYTICSTE LRIGGAASAD GNSTGGTDPV QWAQVEVVLI
KGAAADISNN TVNLIYL
//
