ID A0A267EVK4_9PLAT Unreviewed; 703 AA.
AC A0A267EVK4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 13-SEP-2023, entry version 21.
DE RecName: Full=Adenylate kinase 7 {ECO:0008006|Google:ProtNLM};
GN ORFNames=BOX15_Mlig018534g2 {ECO:0000313|EMBL:PAA65553.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA65553.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA65553.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA65553.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA65553.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA65553.1}.
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DR EMBL; NIVC01001639; PAA65553.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267EVK4; -.
DR STRING; 282301.A0A267EVK4; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0019205; F:nucleobase-containing compound kinase activity; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd22967; DD_AK7; 1.
DR Gene3D; 1.20.890.10; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000850; Adenylat/UMP-CMP_kin.
DR InterPro; IPR047499; DD_AK7.
DR InterPro; IPR007858; Dpy-30_motif.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23359:SF105; ADENYLATE KINASE 7; 1.
DR PANTHER; PTHR23359; NUCLEOTIDE KINASE; 1.
DR Pfam; PF00406; ADK; 1.
DR Pfam; PF05186; Dpy-30; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 589..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 387..439
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 593..633
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 703 AA; 80582 MW; 042E7B1C1EA6E3EF CRC64;
MAAEATKPVR IFVNHVDEYQ GYHISKYLSQ CAVGATLEDN EEEEEEAGSV LSGDFPVKPK
EGCYEIHGTL KKTGAKQPEF VKEILSYDTR EQMYEHLVEC DVIVYDITQD PDQIEEAMWA
LTELHQDIEK LESQKVFILL STVMTWAKSK PADEEDLESP LTEEDYRKRK PHQNYKEHLA
AEKAAVKYGK TKKSRLTTYI VASGLTYGCG ENIFHSFFKA AWHNAFTLPV YGNGQNVLPM
IHIRDLAAVL QNIADSKPKV KYLVAVDDSQ NMLDEVVKAV SVGLCTGKIR TVTKEEAALS
KDIDQATLDQ LMLSLRLDAI YVKENFKINW ACETGIVENI DQIIKEYKKE RGLQPIKACI
LGPPASGKSV IVKQLCDFYK LHHIRAKDVI TEAIANLQRS AARADAEEED DDGKAAEDAE
TLEQVNENMA ENNDRLDDSF VIRFFREKLA SKACQNQGFI LDGFPKTKQQ AEDLFAPDED
DEEEGEDGGG PFNKRLMPDQ LFVLEAGDDF LKRRVMQLPE AVVAGTHNTE EGLLRRLSEY
RAINTEDDSV VMYFDEKEIH PDVFDVSKDD STMHAALVER IKKAIGKPRN YGLTPEEQEE
IRRREETERL ENEKRERDER ERRERQEADE RKRCQEEWAA RLEEVKREEH ELLEIRSEPL
RNYLMKHVMP NLTKGLMECA KVRPDDAIDY LAEYLFRNNP QVD
//
