ID A0A267F036_9PLAT Unreviewed; 491 AA.
AC A0A267F036;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=ENTH domain-containing protein {ECO:0000259|PROSITE:PS50942};
GN ORFNames=BOX15_Mlig009811g1 {ECO:0000313|EMBL:PAA67135.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA67135.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA67135.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA67135.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA67135.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the epsin family.
CC {ECO:0000256|ARBA:ARBA00010130}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA67135.1}.
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DR EMBL; NIVC01001505; PAA67135.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267F036; -.
DR STRING; 282301.A0A267F036; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR CDD; cd16990; ENTH_Epsin; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR003903; UIM_dom.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR PANTHER; PTHR12276:SF110; FI19443P1; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00726; UIM; 2.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 3: Inferred from homology;
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 10..141
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 152..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 242..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 340..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 376..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 436..491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..256
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..403
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..476
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 491 AA; 52356 MW; 453C08B798C5C6D0 CRC64;
MTTIRRNFKN IVHNYSDAKV KVREATSNDP WGPSSTLMAE IAEMTYNVMA YTEIMSMIWK
RLNDKNKNWR HVYKALVLLD YLIKTGSERV AQQCKENLFV IQSLRDFQYV EEARDHGLNV
REKAKQLVAL LKDDERLRAE RAKALLTRER LHQGVGHHTG SGSGRSRMRA PEFAGSGDDL
PASPGAAAAV TAGGGGGVHQ EAEDIELQLA LALSKEEHEQ EMRRREAEGL KEDMKLRMAL
EASKRDEEER QKKGATVTRQ KSGTLVDLID TSLSAAPANA PDPWANSATT ATASIGGGTS
AGDPWSLGSA DPWATGATAS VGANGSSFAI GDPWAKSATA MSATAAPPPL PARQPQSSGS
DLQSLSADLW APAAAQPPDL LSSSNSAEQQ QQPSPSASAS KSVAKNFLSE HGNLVNLDSL
VSAPKAGAGT NPFASGLGGV NPFASSDPGS AGQPTLAELQ QQQQQQQQQQ HHFNMSHEPV
PASAAGLNPF L
//
