ID A0A267F201_9PLAT Unreviewed; 718 AA.
AC A0A267F201;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=BOX15_Mlig022198g2 {ECO:0000313|EMBL:PAA67254.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA67254.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA67254.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA67254.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA67254.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA67254.1}.
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DR EMBL; NIVC01001498; PAA67254.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267F201; -.
DR STRING; 282301.A0A267F201; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19756; Bbox2; 1.
DR CDD; cd00063; FN3; 1.
DR CDD; cd12889; SPRY_PRY_TRIM67_9; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003649; Bbox_C.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR017903; COS_domain.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24099; E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED; 1.
DR PANTHER; PTHR24099:SF15; E3 UBIQUITIN-PROTEIN LIGASE TRIM9; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR SMART; SM00502; BBC; 1.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS51262; COS; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50119; ZF_BBOX; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 170..224
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 237..279
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 387..446
FT /note="COS"
FT /evidence="ECO:0000259|PROSITE:PS51262"
FT DOMAIN 451..543
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 525..708
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 53..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 718 AA; 79183 MW; 9E284C9E9848DD45 CRC64;
MTTMRKLESE LKCGLCRRWL CQPLLLPCGH SLCQSCCSSI LLLPADEVAS LTGGGDSSDQ
MSVASEADSG VSLPTSTASG SGSSRPGSSC YQLHQQQHHQ QHLLGAVASP SSPSAVGFLC
PTCRRPVLLP GGIDRSSSLR NLLPRNLALE RLVGKFAQSH QSQSDLHQPQ QQQLCQLCDP
CDTGQSPLPV ELVCEQCEMY YCQRCAEKSH PSSVSAPKHN LQPASCGREL LLQKQARRSS
VCQEHRQETL GSYCLACRGP VCPMCAQTVR HQGHEIVPLQ TACKSAKTEL SVQLQSLSEK
AKSGSEFHQQ LKSSPERIKA NCESMSEIIA GQFDSLIEAL QSKKQVMLSQ LQSEQEHKTR
LIRDQAAHCG SVLSRTTSLL QFCVEMLKET DPAAFLLVSN SLLHRAVHAE SVFKKDIDLR
PRVSHEFEIR LDVEPVLVAI NSLTFTEHKV PPAPVIIAER SHAENNTVTV CWSPCPGSQA
EFYTLEMDDG RGAGFKRCYR GPETICCVQG LQFDTVYQAR VKAHNTAGES AYSDFVKLRT
AGRAFFQFSP EESHAELVFT NQGMTVTSVS LEERIAVCTT GFSRGVHYWE FTVDRYDDKG
DPGFGVARLD CRKDEKLGRD NRGWSMYIDF KRSWFLHNGE HAERCDGGIA KGSIVGVRLD
CDKGTLSYYV NDEPHGPVAF LDLKGTFYPA VNLNRNVQLT LHPGLEVPSE SDDSSEEN
//
