ID   A0A267F3C5_9PLAT        Unreviewed;      1210 AA.
AC   A0A267F3C5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Mab-21-like HhH/H2TH-like domain-containing protein {ECO:0000259|Pfam:PF20266};
GN   ORFNames=BOX15_Mlig024507g1 {ECO:0000313|EMBL:PAA68216.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA68216.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA68216.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA68216.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA68216.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA68216.1}.
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DR   EMBL; NIVC01001410; PAA68216.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267F3C5; -.
DR   STRING; 282301.A0A267F3C5; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   Gene3D; 1.10.1410.40; -; 1.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 5.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR046906; Mab-21_HhH/H2TH-like.
DR   PANTHER; PTHR24171; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED; 1.
DR   PANTHER; PTHR24171:SF9; L-ASPARAGINASE; 1.
DR   Pfam; PF00023; Ank; 3.
DR   Pfam; PF12796; Ank_2; 4.
DR   Pfam; PF20266; Mab-21_C; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 14.
DR   SUPFAM; SSF48403; Ankyrin repeat; 2.
DR   PROSITE; PS50297; ANK_REP_REGION; 12.
DR   PROSITE; PS50088; ANK_REPEAT; 12.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW   ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          65..97
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          132..164
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          165..189
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          229..261
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          262..294
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          295..328
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          329..351
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          363..395
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          397..429
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          430..462
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          463..495
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          496..528
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   DOMAIN          811..912
FT                   /note="Mab-21-like HhH/H2TH-like"
FT                   /evidence="ECO:0000259|Pfam:PF20266"
SQ   SEQUENCE   1210 AA;  135482 MW;  1BF9993BC3C0F7CD CRC64;
     MPNPTKCLLT TLSTIARCTR GISTGSCQAH RASRLLQQMI QCKDMTRVMR WLEDGRDIEC
     PTHSIGYTLL HAAARYNRVG LVECLIESKA NVNAQSLWGA APLHFAVQKN SLLSLKRLLA
     VPGIQVGIRT RNGLSPLHYA ADNGHLEAAE LLVEAGADMN EQTEDGRAPL HFACLKGHKE
     FALWLIDSGT ANCSLIKKDG KTALHLANFE DIARRLIEKG VGLNTKAVNG RTALFLAAAS
     NNAEVVASLL KAGALVNFAD NKGQTPFHIA CNNNCEEVVR MLQQERLNFN ASDKLGCSAL
     HLAADNGHSE IVYRLLEKKK IRVNSRDCQG RTPLYFAAHR GQIKAVKLLA ECNRTELNIQ
     GNDGNTPLHA AADCGHTEVV EALLKAGCNV NLHNSTRSGV PLHFAADRGF VKIVQLLLDY
     DAEVDAKSSE GWTALHFASR LGRTEVARIL VERGACVNSS GRHGWTPLHV ATRMGHGEIV
     KLLIGKSADV GIELEDGNAP LHFAAQNGHP EIITMLLDAG ASPTQKAHRT SATPIDLAAV
     FNRHVSLKLM LQSLCRKGVD LLNEKSLESL DRTKLKEAQE LLSTDRPQRD TKIRSQELHE
     AMNEAGFIRE RCVTQTAMSH VLEEIIQSHS GQTMCLTGSF SEGWGCSLTR LDGIVDLNSD
     LDMTVFIKGL RYHLKGFCKC TKLKESPEDD NRRREIAERQ RNTLEYSQGH VKFSGHSSNP
     VRNFYGSIKR PAMDEAVAYN CCSYPDMPIL DAKTTKINKV CMDKLNRESL RHNSCHLVSA
     APPGMEGLYI RVSTALLEKK MTRHLNVVQG QVLTILKYLT KSVVNKNKRA LKSYHVKTLI
     YWMVNEVAEE EWMPNNLISL VEKALNKLAE DLEKDYEGVK PHDVMPHFFL PDTMLQLHRD
     GPHRDEVAKT VRNVLGNLNR HLTEYKRLLR PLGPDKLMNF HPFMYIPRSP VSSSGLSSDS
     IEYFALFDHM KRLLLCLTND IQSDKCSLLK DIDAIPVFAK TARECMKALA QLKYGEVDAA
     KGTVEAFVNS GHRVSRGIEV RENAKAVDKE IEHVWRQLRE TDSGYKFCFY IPPPADPNLD
     FVSPRISEWV PLKLLDFDSY YGINFDVLIK SLYLEFFPDH EATKMKWFRE LIDGDLDVKG
     MLMLIEFCSE SELLLDMIHK HKALVAASKI LQDKLVLKIQ DMEELQKQSK TRTLKKLIQE
     ELLDLDSFGW
//