ID   A0A267F3I6_9PLAT        Unreviewed;       952 AA.
AC   A0A267F3I6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Tubulin--tyrosine ligase-like protein 9 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BOX15_Mlig030500g1 {ECO:0000313|EMBL:PAA68335.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA68335.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA68335.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA68335.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA68335.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body
CC       {ECO:0000256|ARBA:ARBA00004120}.
CC   -!- SIMILARITY: Belongs to the tubulin polyglutamylase family.
CC       {ECO:0000256|ARBA:ARBA00006118}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA68335.1}.
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DR   EMBL; NIVC01001403; PAA68335.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267F3I6; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 2.
DR   InterPro; IPR004344; TTL/TTLL_fam.
DR   PANTHER; PTHR12241:SF31; POLYGLUTAMYLASE COMPLEX SUBUNIT TTLL1; 1.
DR   PANTHER; PTHR12241; TUBULIN POLYGLUTAMYLASE; 1.
DR   Pfam; PF03133; TTL; 2.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW   Cilium {ECO:0000256|ARBA:ARBA00023069};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT   REGION          1..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          549..578
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          635..669
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..41
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        635..661
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   952 AA;  108974 MW;  E5E26592189BAACF CRC64;
     MNVPASSASK MTSIVKPSSS ALTSAGTKDC SNNNAMQTKS SPPDEDDFDE TKSSKRRRRR
     KKLKDDFELP ESLPNVFEFS TSLYRFTEHL AEFTKLYQEV FPQLMADKNK YFISTEQQGV
     GCLDLLFETF CKHLGMEKLK NLPNGSGERV FCWLGKRKAS EILPTLRPNH HIVNRLPMDV
     FLKDKQSLAF TLQSSIFQRG IGYPEHDCRH NGGRRLRHQL LCPHQYAEHS FQHCQVPGCF
     EALRLEARAE RQLIDLHNGD LCPCFRANYF VPETRVFASS VQQNVFIEEV SRLAPDSQWI
     VKPSYLRRGR GVRVLPSVKH LKSFLKVETR QRFMWGQDYV VQRYIKNPML TNAGQKFDVR
     MFLLVVVCRF WRVLGFLHPG YVRKVARPYK EMRQDDRFDP REHLANTRIW RRANAVVSTP
     NAPAASGASS QRLKGSSSSI SSAVAAVAAP LPESLNSVND MDDVTSVMNI ADSGVTFNRL
     SAQQASLSTE QVPASLWTQS GFSEWQQQQQ QQQQQQQQAM TLTCPRQQQL NQQLPCAQQS
     QPFQFQQLLQ QRQNSARSRL KTPKKTSKSP EPFEPVPLTG FFRQSFESDE CEEFNYAVRH
     GCLKGNRANL PLLLGTMRIP GARHLAASLP TAKMSAKQQN WSSAKPQSKS KPTAGNKQGK
     RKQSSVRMRA TETRELLEPF IMNKYFIRRL QQMATRICEG VFDQVKEKSN CYQLFSLDIC
     IDSFGDPWLL EVNPTIITED VNWNSGTIRQ VVPAVFSESL GLAHECTRKS LNFLALRTPS
     SYQRKPNDLV FRQNFLWMYN TPAKSCEMSE LKSLKYGVDS MHKQQLASRG IEYVPVDYYP
     KRNLRRISKK ESRQLNDQKK QPKSIAAASA ASRCIYRFPS PVRSVPVLEE DLAHSTRYMR
     LQPDIVGRQL MVRQIEAEAR ARQKETMARR CATHQDSLAK RSVTVRHRVQ AD
//