ID A0A267F959_9PLAT Unreviewed; 525 AA.
AC A0A267F959;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=C2 domain-containing protein {ECO:0000259|PROSITE:PS50004};
DE Flags: Fragment;
GN ORFNames=BOX15_Mlig011884g1 {ECO:0000313|EMBL:PAA69609.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA69609.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA69609.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA69609.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA69609.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the copine family.
CC {ECO:0000256|ARBA:ARBA00009048}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA69609.1}.
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DR EMBL; NIVC01001308; PAA69609.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267F959; -.
DR STRING; 282301.A0A267F959; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:InterPro.
DR CDD; cd04048; C2A_Copine; 1.
DR CDD; cd04047; C2B_Copine; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR037768; C2B_Copine.
DR InterPro; IPR045052; Copine.
DR InterPro; IPR010734; Copine_C.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10857; COPINE; 1.
DR PANTHER; PTHR10857:SF106; NICOTINIC RECEPTOR-ASSOCIATED PROTEIN 1; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF07002; Copine; 1.
DR SMART; SM00239; C2; 2.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50004; C2; 2.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 1..119
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 121..259
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PAA69609.1"
SQ SEQUENCE 525 AA; 59090 MW; C606057CADF8F4E9 CRC64;
TFTDMAAPQL TSRVEIIVSC KNLPDRDVMS KSDPMCVLFM KTPTSTHEFG RTECIQNTLN
PQFNHKFQVD FCFEERQVVI FRLYDVDSSR AALQDHDFLG ELETTVGELV SRRQYEAALT
KTGSTKKSLI ILTCLELQEC KLIANFRVEG VKLDKKDFFG KSDPFLEIYQ PMDEIQTESE
VPRVRSWVLV HRTEFIKKNL NPKWAPFSIP LNRLCRGNRQ LLLRFDCHDY DSDGSHDFIG
SFYSSLESLE QEVARSRSAQ RTLISKKKKS AGTIVFSQIG IETIDSFVDY IQGGTELHFT
VAIDFTGSNG DPRDPRSLHH VSADGRPNQY ELAIISVGEI VQDYDSDKQF PGLGFGALLP
PMFSGVQDAF SLTLQPENPY CAGMPGLLAA YRSCIRAVRL YGPTNFSPVI NHVASMAAAH
QTGAQYFVLL IITDGIITDF EKTKQAIIKA SFLPMSIIIV GVGDEDFSAM EELDSDDKRL
RCGSMIAERD SFLCVASFRV AALIAAGMPW RRRYWRSFRI RCASG
//
