ID A0A267FBE1_9PLAT Unreviewed; 446 AA.
AC A0A267FBE1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=ACB domain-containing protein {ECO:0000259|PROSITE:PS51228};
GN ORFNames=BOX15_Mlig003904g1 {ECO:0000313|EMBL:PAA71078.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA71078.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA71078.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA71078.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA71078.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA71078.1}.
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DR EMBL; NIVC01001186; PAA71078.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267FBE1; -.
DR STRING; 282301.A0A267FBE1; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR Gene3D; 1.20.80.10; -; 1.
DR InterPro; IPR022408; Acyl-CoA-binding_prot_CS.
DR InterPro; IPR000582; Acyl-CoA-binding_protein.
DR InterPro; IPR035984; Acyl-CoA-binding_sf.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR PANTHER; PTHR23310; ACYL-COA-BINDING PROTEIN, ACBP; 1.
DR PANTHER; PTHR23310:SF77; LD25952P; 1.
DR Pfam; PF00887; ACBP; 1.
DR SUPFAM; SSF47027; Acyl-CoA binding protein; 1.
DR PROSITE; PS00880; ACB_1; 1.
DR PROSITE; PS51228; ACB_2; 1.
PE 4: Predicted;
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 408..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..116
FT /note="ACB"
FT /evidence="ECO:0000259|PROSITE:PS51228"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 183..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..322
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 48611 MW; A7D3538BBA979562 CRC64;
MSADTSPDSQ HRNASSRSPL AQFEAAVQVV DSLPRGSSSQ AVAMQGFKPS TDLMLRFYAL
YKQASNGPCQ QPRPAFWDLI GKMKWDAWRA LGDMPRERAM LEYSRQLRTV IESLPNSSPA
VSGLIDKVAN FYRLVDDDDD QESEVKLGLL LANRIRCRSG GNLDAESAAA ADLDVNSNFL
TQSLPPKITS SSSNDNRNGF LRNSQPNPRR RQASETSVWP AAAVVASAAV DPEHPDRGGG
GSSSSSSDND EFCDSYDNFV QPFGDDQPGD VTGGQQPSTS PSSASAAAGG GHQSAGRRQG
RQQQQQQQLP SASSFENSNG LSWQPPLPPP PDPTGRSAAA ASSFELEREL VGQLRHIRAA
LDRLSGDLGQ IHTRLDRLER TSHKSALSDS SGSFYCWFQR WLFSGRGVGG LSVPALLLLL
AWPVLVQLLW RLPWRRLRQR RGRLAL
//
