ID A0A267FE80_9PLAT Unreviewed; 1951 AA.
AC A0A267FE80;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
DE Flags: Fragment;
GN ORFNames=BOX15_Mlig007002g1 {ECO:0000313|EMBL:PAA72003.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA72003.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA72003.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA72003.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA72003.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA72003.1}.
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DR EMBL; NIVC01001121; PAA72003.1; -; Genomic_DNA.
DR STRING; 282301.A0A267FE80; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF185; ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 467..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 548..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 580..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 646..669
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1051..1074
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1315..1336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1357..1384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1396..1416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1428..1451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1463..1484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1505..1531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 711..934
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1573..1793
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1874..1902
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1925..1944
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1929..1943
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PAA72003.1"
SQ SEQUENCE 1951 AA; 214685 MW; E64C3E28C4DFDA01 CRC64;
FQLFNFSLKL SLPEALCNAG KLQSLIDFSN VTYNVSSLVE QLCVNRTLRD VENITETILK
MGNFGRFFMK QFGQQAIDSL LNSSGVTLVD LKDAIQAVQD TGNALQNAFN VLQELVGVVA
SFNPGSSDMG SPNGLEGISQ AVCGTSGKFN FTSVYGISLS PGSTDSGRRR KRRSTHSTTY
TYELGQLASN EFCRNLYDLT QKSTAGRVGW TYVKPIIRGR VIVTPDTNTT RSLMSGAQEQ
FTKLFNLQEL ANSLAGLLPT ATGTSAASVL ANLLSNPLAS SAFSGILGSS TNLTSMQNLL
KVFTGNTTSN SSSTNQMLKL LQNFTSCIET SRLDYYATGS SQYDAGLQAA LSENRLLAVI
DFENLSSSRR RRDVAPGSSG LPAHVKYTIR MSYGTLYQTN TLMSYPEIYE KRSSFMFDLA
YQRGFVQIQE SIDRTIVRMQ TGRDMPAQQT KQMPTPCLQK DSMLRSFGLA ILPISTIFMW
LAPLAIAIQQ IMYDREHSLE IPLFLMGLRP SIHFLQWFLV QLLNMLILSV IITIACVYGG
LLSGTDPSII FVLFGLFSFS SLGFGYMVSA FFITSSVACV IALLIYLLMF VPFVFLSYLH
IGGTALQAVN IFSPTAFSLA SRSIVTLQLA NSKVHWSDIM KETYGIQVYG SFLALALDGV
VYFLVGWYFR NVLPGKHGVP QSPLFFLTAR YWGCDSSRKK SDTSSAAGAV VELKNVNKKF
GSKQAVQNLN LKLQENETTI LLGPNGAGKS TTINMITGLI SCDSGKITVN GLNVSTSFYK
LRSSIGFCPQ HNVYYDDLSV KQNLAYFGAL KGCSKSELED MLRWLRLYKV RNVAVQKLSG
GQKRRLSIGL AFLGKPSLVI LDEPTASVDP DARRTIWELI KAHRCTTLIC THDMQEAEIL
GDHVAVMKDG CIVDSQSYQN LFENCRYTID ISSESPQALA EELSAQNLNT SEPAINERHK
KVQLTCPKEG RVMASLTYSL DRLKTAKQFV TWFSITCSTI SDYFNDIIFG KEVIQDSPQS
IQYQKRAGKP STGVKIGALF GKRFHHAKRS WISYIGMLIL PCVFIVFTMG STLLRPSFSQ
ESAKLLLTPT IYGPGAVTFL YQDAGFPMKE AVRSSLARPP GIGTVCMPGE NRGKTPFFTA
PCKETSATWD LKNFTAAKLA KYATYRNCSC DKSSHYECVD EYSKGTPPDV LVTPSGDVIH
ELRETTNLND LLLRSTARFN LSGPRSVSIA PAANQRWGGL ELQSNSSVIW FDNRGYHTLP
SYLNAYSNTM LRMFVATSNY SNYSSDYGIS TYNHPLPMQR SQLNTETFDL AIKDAGLAMC
IVFALCFVPA SISLTVSNER FSGEQVHLRL YGVGIPTYWL TSFVWDILMY LLPLGIVIGI
MAAFQIDLYT ANLNLPAIAM LLALFGMSAI PLSYLVSRMM RSPAGGFLLS FFILFFVGIV
LFSLLLLLQF YVNFTDKELT LQILTYVFMA LPSFSLGNGV FQVVENQWKA SILKSYGASE
YADPFTMAMV GPHAIAMGVG CVVFLLINIL IDIRCRGRNR QARLSYLTDG GSDVGVQEEF
DRVNSGACRQ DPIQLTGLGM TFRTVRGFRI HALDNLTMSV AEGTCLGLIG PNGSGKSTTF
NILTRQLNGY SGYCSIEGLS YCPQSNPLDK EMTVTETLVF YARLLGLSSK DQDVQLEQLI
SALRLPPNKV TKALSGGQRR KLSVAIAFLG APRCILLDEP SAGLDAVSRA ALKQLVRCVV
SQGSCVLFTS HCMEEVEGVC DRVAILIGGR LRAIGSMDEL KEQLGRSFTL TVRGSRDDKE
QLTKYLQNAF PNAECKMSAA GVSEYAVPIT TKLHEIFKAM EKCAQDSLCS EYTVKQTTLE
QVFLELCSHQ TDSWREEGSA SGSGSQPSGS SDSPPSSSAG LTALMKRSSW KQSIDSRDGL
DYNLDLDKSG TMRSASQGEG SERTNIYKVY L
//
