ID   A0A267FGS0_9PLAT        Unreviewed;      1772 AA.
AC   A0A267FGS0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=FRAS1-related extracellular matrix protein N-terminal domain-containing protein {ECO:0000259|Pfam:PF19309};
GN   ORFNames=BOX15_Mlig031119g1 {ECO:0000313|EMBL:PAA72956.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA72956.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA72956.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA72956.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA72956.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA72956.1}.
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DR   EMBL; NIVC01001050; PAA72956.1; -; Genomic_DNA.
DR   STRING; 282301.A0A267FGS0; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   InterPro; IPR039005; CSPG_rpt.
DR   InterPro; IPR045658; FRAS1-rel_N.
DR   PANTHER; PTHR45739:SF12; CHONDROITIN SULFATE PROTEOGLYCAN 4-LIKE ISOFORM X2; 1.
DR   PANTHER; PTHR45739; MATRIX PROTEIN, PUTATIVE-RELATED; 1.
DR   Pfam; PF16184; Cadherin_3; 6.
DR   Pfam; PF19309; Frem_N; 2.
DR   PROSITE; PS51854; CSPG; 4.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           29..1772
FT                   /note="FRAS1-related extracellular matrix protein N-
FT                   terminal domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012492686"
FT   DOMAIN          39..141
FT                   /note="FRAS1-related extracellular matrix protein N-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19309"
FT   DOMAIN          168..265
FT                   /note="FRAS1-related extracellular matrix protein N-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19309"
FT   REPEAT          846..937
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REPEAT          1078..1172
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REPEAT          1194..1294
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REPEAT          1574..1667
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REGION          336..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1772 AA;  197683 MW;  E37835F4765838C3 CRC64;
     MAATSMQHLL PVLLWLAVLI IDVTSCSSAT VVVPNASRPP IRVQQGKSVA LTAAHLLIRR
     QPSGSGSLCR VEVDSSDPLT QTVGQMKPKV FDCYFTEGSV FYEHEGSPLR SHDSVRLLVY
     SFQPGNRSEI APIRLAVEVQ LRSRRGSGQG AVGERSSSTA TYIVMPGPRP LTVPRFRGTS
     APIDSNALNF VYDPLTTRCT VVYSDSVQAS SSLAFRDWPM VGRLVDDQST RVREFKHDCR
     QFLLAGYRYE HQRPPNPDMD YIPLSVYLLR LDFNGSVDAT SDAIVTEKYY LPVHIDKAQK
     SAPPQLQLRQ RSVSLAHTGG LPVVLPADLL LLPSASASST TSDSAPSTET DIRRSGDSSG
     GITSGLVVMV TQIEPVLPFN INASFVDTRE PTAGQISGFQ PRDLREGRVA FQFATPTDTD
     RVELRIRLRP IDAFFQDGPD VLLNLASTPN RQLQLFPRPL LAYTQATVRF NSRNLLCSGS
     DCNLVSYRIR REPYSGRILM NNAPIEFFGP RTLNNPEEFY ITYTHNGNIP SEDSIELRTQ
     VSKSSGTPIV FKFPIHVTRL WDSVSTLKSS NVNYRLGPGG QVCFGVEIID ESVLRTLKHD
     CIDMRYEVVK RPEYGNLIRA LNPLSDWARS RSTSTFLTFA VSDLLQGKTI CYLQQRNLEP
     GQTNVWDSMT LKQAGRPDFT PLLIRLRLHD KPRAPLINRS ARYLSAPTML ETDNNFVITR
     DFLRYETEGL SPNQIVYEVL LHPYYAGTNI SIDAGRLLDK RKLERIFTTG DNVKAKVRIT
     SFKEVGCLSQ FTQEDVDNGN VLYVPPLNDV GISNRTVNVY LQPYDTTWNK ASPHKLTFIV
     LPVDNQEPKL EPQKLSVERG KRLTIKLNHL RPRDIDTKVD QLTLRLLKEP KHGKLYDGDV
     SIGVGQWFKV GRVRSEKISY QHDGTTSSAD YFVLQVTDNN QNSPDYNIYL NITERQAWDY
     GTKFYANNTI FVLEGGQTVL TTEMFPTLKS ETIDPRQISY LQGERPVKGE FELLGSSSRS
     ISQFNHEDLR AGRIVYRHTT GEIGPRAIVD ICPMFVYSGS DWQTHRLTFS IQPVDNQPPS
     ITDGAQVLVK EGDSTVLSGN VIKVRDADTE ADKLLLMVQD APKHGEIRLI NGSGATVNQF
     SQQQLLAGEV AFLQNKNFGT EFTRDNFTVI ASDGERRSSP VTVQVYIYPV TDELPSIVGL
     ADFAISKGES RVLNATYFSV TDADVPEEEV IVRIRRLPSV GTLFQDWFTA RISKKVTETS
     NRQFTKRNLN YMRLVYHQDL DVTSLNDSFV VEASDPVYRI SKTCRIAIAT RNEQPPVFSS
     PRSQLQLYYG EKVQLTENHL LVRDPDTPKE AISISVVSLP ANCELLRLEP SRSSVILSGR
     SRDRLVALRL GESFSQRDVQ QSRMFVRASR LSSSSAASPA TVELRLMAGD GRFSTDAANL
     MLRLVPKPAE VLELFLIRTS RLKAVTQRVT KLTQEEISVY YRDRVQNSAS FQVIPQQVSD
     SQPCYSFELE GDPVVTDNET VFLMSDVLDG RVLFNATNCS KSKEDILFEV RSNWIGKSAS
     GMLPVDLIRL DVAPPTLDHV GTLSLRAHEA VAIDQTVLRT SDADTPPQEI LYRIKNAPKQ
     GLLVIGNSQL GQEDSFTQAD VNNGTVLWYR SLIEPPTGLD KLKFTVEDMN KTRGFCYKSA
     IPRSSPVTLS IRVAPSTRNP IELVRVKSPS ELMSFGNGGR FGFRIKNDSL LAKPAMVLFE
     LASQPGLGIL KLGESEIPVG GVSLSVTSIP DE
//