ID   A0A267FKJ1_9PLAT        Unreviewed;       370 AA.
AC   A0A267FKJ1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Tetraspanin {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=BOX15_Mlig004015g1 {ECO:0000313|EMBL:PAA74315.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA74315.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA74315.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA74315.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA74315.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA74315.1}.
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DR   EMBL; NIVC01000957; PAA74315.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267FKJ1; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR008952; Tetraspanin_EC2_sf.
DR   Pfam; PF00335; Tetraspanin; 1.
DR   SUPFAM; SSF48652; Tetraspanin; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        35..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        92..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        151..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        348..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:PAA74315.1"
SQ   SEQUENCE   370 AA;  41336 MW;  59E4737473EA1C56 CRC64;
     CKYFYNLCFQ EFPYFKQLSF LTLAMSSVSL ECYQLMLLSL RLLPSFFIIC FGAVVLMFRI
     DMGLSKTDLD TITQFLTKDY SVINGVNLGK PLFWTTIGLV CFLLWIALHL MLLVLLQIAG
     VERPAALMRF YPNYLSHKLK RRRAVSDTAN FIYFAGAITF VVSLAIGLCI CLSARRDITD
     AKKVNLAESI RKAMLSFKLK PWQGVNKTQR LIDNIQMSFG CCGLNSYHDY ALEPRQTGIS
     WERHFYDRSM AAVAAGLQQG KHLVARPPAQ SCCLQTDTGK QLNCTVGDAT EERSGDPAVD
     VAAVAKSSNS SGAGTGAVSA RKTMKLHKLG CYIRVLQYIR HRQAEAEYWS FVIGACIAAM
     GSMAYWAQAM
//