ID   A0A267FM58_9PLAT        Unreviewed;       888 AA.
AC   A0A267FM58;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=BRCT domain-containing protein {ECO:0000259|PROSITE:PS50172};
DE   Flags: Fragment;
GN   ORFNames=BOX15_Mlig030250g5 {ECO:0000313|EMBL:PAA74890.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA74890.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA74890.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA74890.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA74890.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA74890.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NIVC01000916; PAA74890.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267FM58; -.
DR   STRING; 282301.A0A267FM58; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:UniProt.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   CDD; cd17731; BRCT_TopBP1_rpt2_like; 1.
DR   Gene3D; 3.40.50.10190; BRCT domain; 5.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   PANTHER; PTHR13561; DNA REPLICATION REGULATOR DPB11-RELATED; 1.
DR   PANTHER; PTHR13561:SF20; DNA TOPOISOMERASE 2-BINDING PROTEIN 1; 1.
DR   Pfam; PF12738; PTCB-BRCT; 3.
DR   SMART; SM00292; BRCT; 4.
DR   SUPFAM; SSF52113; BRCT domain; 3.
DR   PROSITE; PS50172; BRCT; 4.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT   DOMAIN          161..230
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          254..343
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          443..537
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          750..842
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          347..375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          408..443
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          546..571
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          590..623
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..49
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        408..432
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:PAA74890.1"
SQ   SEQUENCE   888 AA;  95879 MW;  7F95426E9F71609F CRC64;
     QSEAKVNPKA DTTARSYPMG LSGKQQQQQQ QKQQQQKPPS STSSSAMSTA SSAAAASLGT
     VYFVEPTGGS RHGLLREAFS LLDGEPSCSA VWLPEAQVPS VLAKHQQRSG GSGRAYFVFE
     DFQGAAYERA AAAPGCRLFG AQLLLQYLRD DLPLPKWEVP LFSAALKDLQ ISVSGIEDRA
     TVKRKIRMLH GNFQPDLTDD VNVLITTCTN SKKYLVAKQF NIKVLLPEWL DGLLAWSRSR
     SVVEPFGLPD FARYVVPPFH NVTATTTNFE QTEKDLIQRL VVKNGGRYTG NLVVGECTHL
     IVARPVGQKY NYARNWKINC VSLQWVVDSD RKQCCLDIAD YLVSDDGKNR AGAKPANSST
     PDKQRVPLSG KTAPDVSCLL DPDRSRVNET VASVPGDRSV CYPVSSTAAS TASAPTSQPP
     VSAASSGIDK ENNFRIPNPP QPQPLAPLRD LRLLIACCRG QQAELQRLTS MARQLGASPI
     SASSNQRVVE ADAGLIIEPD QLEDLPAGVQ CGVLVAKQWL LDCSEKQQRL PFDAYKLLWR
     QPAAADEAHE TGDSTMGPGD AAPAAAAAPP ASDMLEESLN ILCDYVREEE SQLKQQEQQA
     AEQDDEEGDE TELPPVRSVV DNNSTAANVL PETEEPANSS TAADTQSFLT GRRVGILGLE
     PAAAAVAARS VTRLGGQVAS AAAAEATQLD LAVLPVVYQR GSGGATEAGL LSADELVTDA
     WLADCIDGPA VMVADPDSEP WYRPCVLSAT ASKPLAGVVL CVSGFELRDR ERVTTLGRGL
     GAIVQENLSR VSKPDRQLRV TTHLVLAASG GHKYSAAMGW GSVHCVTKHW LGECGRQGRR
     LPRLSSTSTR WPITRSENGA KLQPPPLRPC RRQCPRLRIP QRLRLLPW
//