ID   A0A267FTA8_9PLAT        Unreviewed;       465 AA.
AC   A0A267FTA8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   22-FEB-2023, entry version 13.
DE   RecName: Full=V-type proton ATPase subunit S1/VOA1 transmembrane domain-containing protein {ECO:0000259|Pfam:PF20520};
DE   Flags: Fragment;
GN   ORFNames=BOX15_Mlig031170g2 {ECO:0000313|EMBL:PAA46716.1},
GN   BOX15_Mlig031170g5 {ECO:0000313|EMBL:PAA76484.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA76484.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA76484.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA76484.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA76484.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the vacuolar ATPase subunit S1 family.
CC       {ECO:0000256|ARBA:ARBA00009037}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA76484.1}.
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DR   EMBL; NIVC01004731; PAA46716.1; -; Genomic_DNA.
DR   EMBL; NIVC01000816; PAA76484.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267FTA8; -.
DR   STRING; 282301.A0A267FTA8; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.160.110; -; 1.
DR   InterPro; IPR008388; Ac45_acc_su.
DR   InterPro; IPR046756; VAS1/VOA1_TM.
DR   PANTHER; PTHR12471:SF7; V-TYPE PROTON ATPASE SUBUNIT S1; 1.
DR   PANTHER; PTHR12471; VACUOLAR ATP SYNTHASE SUBUNIT S1; 1.
DR   Pfam; PF20520; Ac45-VOA1_TM; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..465
FT                   /note="V-type proton ATPase subunit S1/VOA1 transmembrane
FT                   domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011916146"
FT   TRANSMEM        418..444
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          412..450
FT                   /note="V-type proton ATPase subunit S1/VOA1 transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF20520"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:PAA76484.1"
SQ   SEQUENCE   465 AA;  47125 MW;  93E57E9519544FF7 CRC64;
     HQLALLAFLA SLACASASVP AVVVSSRGSV DSLASLSSAR LNSQQLAEAL HRSAGGLLLV
     VTVDEGLSLP DFARSGGDVY SAGQGSASPF ASVAGLSEKL GGRHLLVAEA DKLLPALRSL
     DWRGGAPIDV ANDGKEVDRV VEAATAAGGA SRLVLARAAD AGAADRLLGA ACAALQSRGL
     PFVAVFTATH ESDPAPAAAD AAASAEAAVS AGRHLLAAPT ASPSSNGTFV NCSSDVLLYF
     ASLQVQLTQN SKVKTLPPVL PVADGSSIID TKLSTCNAAG GNRTLALSFP DSALQSPLAA
     LKLTLNFVGD TKSSTSPWSI ASGTASLSCK SGSSANCTNV AETALTQESL ASFITPNGSC
     YHCTNNTRLS TSGGTGSNGS AALTLIFGKF QLQPFGIPAD GKFSKNVNDC VGFFSVEVWF
     SLLVLLVITV ILMYGVLMLV SVATPDRFDD PKGKTIQVNV QDGGN
//