ID A0A267FTB3_9PLAT Unreviewed; 559 AA.
AC A0A267FTB3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
GN ORFNames=BOX15_Mlig009463g3 {ECO:0000313|EMBL:PAA77035.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA77035.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA77035.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA77035.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA77035.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA77035.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NIVC01000769; PAA77035.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267FTB3; -.
DR STRING; 282301.A0A267FTB3; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR CDD; cd00174; SH3; 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 4.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14167:SF114; CAP, ISOFORM AC; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF00018; SH3_1; 2.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00499; P67PHOX.
DR SMART; SM00326; SH3; 4.
DR SUPFAM; SSF50044; SH3-domain; 4.
DR PROSITE; PS50002; SH3; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 285..348
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 368..428
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 501..559
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 131..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..96
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..191
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..207
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..258
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 559 AA; 59391 MW; E49C69DEB3817482 CRC64;
MSRVIKSLRN LDIGSPLSSK PGKLEENDNE QRQQQQIAAA ESGSGKSGGG LLSRLKPGKQ
KSYENLLDAG SPTEERPKQR QSPQSGWATF EDSANLIDLS SPLPPAPPPV STQPTFFIDA
SAPRTQQPLI IRSDNGRHGG SLECLSVNPG GGAQALFNPS FRKESPKAKA APAPPPASSS
SATQLRATRQ TPPPRPTQPP PRPSQPPKVT SSASSNALLL LDLDFGHPQQ QQQQQQPPQP
AAKSRKAPAP PPPAHQQPFK RQPQQLPQTQ PPQPELAPDL TGHLTPGSVC SAKFDLANPP
DPGILSLRRG DLMTIVRRED DNWMLARRLT GDCLEGLVAC SYLAPAKDSP APSPPSAAAP
SPPAAAESLA TKARSLHEYK SDHPGDLSFP AGQLISEVRR VDSDWLEGRL GSGPRGLFPA
NHVRLILYPA TAAYAFPAQE AGDLALQVGD SVDVLAELPG GEWLRGVRRR RPGEADNGGV
DEEAGNFPAA FVVSEESAAA EPAPSARAIH DFAGRESDEL SFQAGDLLTS LTELGPDWLS
GMAADGRRGM FPRAFVELL
//
