ID A0A267FTL6_9PLAT Unreviewed; 1120 AA.
AC A0A267FTL6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Desmoplakin SH3 domain-containing protein {ECO:0000259|Pfam:PF17902};
GN ORFNames=BOX15_Mlig006129g1 {ECO:0000313|EMBL:PAA76302.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA76302.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA76302.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA76302.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA76302.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA76302.1}.
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DR EMBL; NIVC01000830; PAA76302.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267FTL6; -.
DR STRING; 282301.A0A267FTL6; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.20.58.60; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR043197; Plakin.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR Pfam; PF17902; SH3_10; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 222..282
FT /note="Desmoplakin SH3"
FT /evidence="ECO:0000259|Pfam:PF17902"
FT REGION 89..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 401..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 507..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 983..1010
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 445..472
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 89..109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1120 AA; 121698 MW; 60C948669196AC94 CRC64;
MTAVVSRKWS QSNPDLSVSH IGLQRSLESL NGEAGMGNSK AFDSNRSFGE QMSLTNKRSK
LVYMDKIAAL ELQLSSLVNA VSDRAAELNS SSSRGSLGGG QSQPGSTDSM PKVDEVATCW
SWIVQLSRLS QIHITYAAEY HKFFYEAREI GAQLEQEKAR VFADLTSNDR RSLGSLPFEC
RRLSGCMRSH LSRLILLGQR AQELSGRSGS VQPVHHRTPG RTADSTSRRA VALCSYTSPE
GQRVVLDEEL QVVDMSDRHV WRVEKSASNG GGQLDLPSVC LALLGPDQEA LETMSRLRDT
IIAVWVQILT SYKQHVGDLL RSFLEFVNME KYTTDSDAAE ASLYTFLSEV ESSYMCYLSG
TEAAAMARLL NQIRARRAPP SDQAVRASRE RRLSNVSLSS VTSTEGFSSG GGGLSRNDSL
RNSGRRTRSL KESEVIQPRA LLKVLNEHVE ALERLRNRRL ESNTEASTKQ DEAALNSPGF
SVPEIRIETD SSVEQSTNVY VFSNQTDAEK LTKQQPPISQ SQGRTRNFST ASARTVTSTV
VNEEVHQLLQ AGVATGSGDV TDGRRSVVRS SSAIGEPSPS TEPKQHVSRM YWMVNQPTRV
EREIHRAELM VHRRLAVDLP HRNFVSAKRI EIGGDACDGV RAVTRVECNY PPRRSVVDSG
ASLDIDMESR GAQTLGDFKE VRPTSALSTQ TLAPVSSECG AFLDFVSEDT GVRAAEEQTP
KSDQPAQTIG EFKEVRPTVA LATQTQPSLA SECCAFVDLD YVSTGVRKVE QPPPTFETSA
QTVGEFKEVR PTVALATQTL PPALGECGAF KDFVSLETGI LAAEKPPPTF ETSAQTVGEF
KEVRPTVALA TQTQPPQLSD CGALRDFSSL QTGVRAAEKS IPKFETSAQT FGEFKEVRPT
VALTTQTLPP TLGECGAFKD ISTLESGVRA AEKPIPKSET PAQTTGEFKE VRPAVPLATQ
TQKPTASECG AFLDFASVES GIRAAEKPPS RSHSSAQTPV PEPGRKANVR VAPAPPPIAE
CGSQLVAESL TSLAKCRPSA DAFANASSQA NFQLELVARL TVRNHNLEDA RLLSVDRSVS
ERPENDGLVS DEQVRLLSSL GLVCSEWSEL DSKHRAPGSE
//
