ID A0A267FXC8_9PLAT Unreviewed; 337 AA.
AC A0A267FXC8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=GST C-terminal domain-containing protein {ECO:0000259|PROSITE:PS50405};
DE Flags: Fragment;
GN ORFNames=BOX15_Mlig005601g1 {ECO:0000313|EMBL:PAA78490.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA78490.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA78490.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA78490.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA78490.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the GST superfamily. Mu family.
CC {ECO:0000256|ARBA:ARBA00005861}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA78490.1}.
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DR EMBL; NIVC01000684; PAA78490.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267FXC8; -.
DR STRING; 282301.A0A267FXC8; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0004364; F:glutathione transferase activity; IEA:UniProtKB-EC.
DR CDD; cd03190; GST_C_Omega_like; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR040079; Glutathione_S-Trfase.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR047047; GST_Omega-like_C.
DR InterPro; IPR016639; GST_Omega/GSH.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR32419:SF6; GLUTATHIONE S-TRANSFERASE OMEGA-LIKE 1-RELATED; 1.
DR PANTHER; PTHR32419; GLUTATHIONYL-HYDROQUINONE REDUCTASE; 1.
DR Pfam; PF13410; GST_C_2; 1.
DR Pfam; PF13409; GST_N_2; 1.
DR PIRSF; PIRSF015753; GST; 1.
DR SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR SFLD; SFLDG01206; Xi.1; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS50405; GST_CTER; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 179..306
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
FT ACT_SITE 69
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR015753-1"
FT ACT_SITE 202
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR015753-1"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PAA78490.1"
SQ SEQUENCE 337 AA; 38339 MW; 4BFAB69CD06F1344 CRC64;
LLARISVASM TTASSSTGQE VGTSWTKSVS GKGEYVRKAS QFRSWISSDK SSEFAAESGR
YHLYVCYACP WAHRTLIVRE LKGLTDAITV NVVDWYLKPG GWRFSPDKPE CTADDVNGFN
TLREVYTSVD PDYSANITVP VLYDKKKRTI VSNESAEIII MLNSAFNGVC GRADLDLYPE
ELRAEIDSVN EFVYNNVNNG LYRAGFATAQ EPYDEAVTKL FNALDDLENR LSTRRYLVGS
PKSRLTLADV RLFTTLIRFD WVYHQHFKCN LRQLVDYPNL WKFTRDIYQL PGVSGTVNKE
HIRKHYMMSH AQINPHGIVP IGPQFDLDKP HDREKLS
//
