ID   A0A267FYN2_9PLAT        Unreviewed;       365 AA.
AC   A0A267FYN2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PAA78863.1};
DE   Flags: Fragment;
GN   ORFNames=BOX15_Mlig024139g2 {ECO:0000313|EMBL:PAA64004.1},
GN   BOX15_Mlig024737g1 {ECO:0000313|EMBL:PAA78863.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA78863.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA78863.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA78863.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA78863.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the galactose-1-phosphate uridylyltransferase
CC       type 1 family. {ECO:0000256|ARBA:ARBA00010951}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA78863.1}.
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DR   EMBL; NIVC01001793; PAA64004.1; -; Genomic_DNA.
DR   EMBL; NIVC01000662; PAA78863.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267FYN2; -.
DR   STRING; 282301.A0A267FYN2; -.
DR   UniPathway; UPA00214; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0008108; F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0033499; P:galactose catabolic process via UDP-galactose; IEA:InterPro.
DR   CDD; cd00608; GalT; 1.
DR   Gene3D; 3.30.428.10; HIT-like; 2.
DR   InterPro; IPR001937; GalP_UDPtransf1.
DR   InterPro; IPR005850; GalP_Utransf_C.
DR   InterPro; IPR005849; GalP_Utransf_N.
DR   InterPro; IPR036265; HIT-like_sf.
DR   NCBIfam; TIGR00209; galT_1; 1.
DR   PANTHER; PTHR11943; GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR   PANTHER; PTHR11943:SF1; GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR   Pfam; PF02744; GalP_UDP_tr_C; 1.
DR   Pfam; PF01087; GalP_UDP_transf; 1.
DR   PIRSF; PIRSF000808; GalT; 1.
DR   SUPFAM; SSF54197; HIT-like; 2.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          2..188
FT                   /note="Galactose-1-phosphate uridyl transferase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01087"
FT   DOMAIN          197..361
FT                   /note="Galactose-1-phosphate uridyl transferase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02744"
FT   REGION          1..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          78..99
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        36..50
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        178
FT                   /note="Tele-UMP-histidine intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000808-1"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:PAA78863.1"
SQ   SEQUENCE   365 AA;  40767 MW;  B32ED8855E4E4DE8 CRC64;
     KPEDHPHRRF NPLTGDWVLV SPHRAKRPWQ GQTERREAGP SESSASLHAN PLCPGATRSS
     GAVNPNYTGT YLFDNDFPAL MPDTPAPPPP LLPSADGADA DSDCGGGLFR MSQARGRCQV
     MCYHPRSDVT LARLPKADTE QVIRAWMAAL TELAADYDWV QILENRGAVM GCSNPHPHCQ
     IWSTAYLPTE AAKKDSNQLA YAARNGNRPM LVDYVQQELR REERIVFQNE HWVCVVPFWA
     VWPFETMLLP RRHVLRLTDL NDGEVSGLAE ALKCLLTKYD NLFECSFPYS MGFHGAPTGS
     RLSGESGHWQ LHAVFYPPLL RSATVKKFMV GYEMLAEAQR DLTPESAAAR LRELPGDRHY
     AGDLS
//