ID A0A267FYR6_9PLAT Unreviewed; 648 AA.
AC A0A267FYR6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
DE Flags: Fragment;
GN ORFNames=BOX15_Mlig021885g4 {ECO:0000313|EMBL:PAA78970.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA78970.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA78970.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA78970.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA78970.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA78970.1}.
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DR EMBL; NIVC01000658; PAA78970.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267FYR6; -.
DR STRING; 282301.A0A267FYR6; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR24064:SF530; ORGANIC CATION_CARNITINE TRANSPORTER 4; 1.
DR PANTHER; PTHR24064; SOLUTE CARRIER FAMILY 22 MEMBER; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 206..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 476..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 507..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 568..585
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 159..590
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 42..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PAA78970.1"
SQ SEQUENCE 648 AA; 70406 MW; AF080DC3A1E0A825 CRC64;
PLHQAGSLSG HSTKQDHYQA TPPSRIIIRP LQTYQDHYQA TPNLSRSLSG HSTKQDHYQA
TPPSRIIIRS LQTNQDHNYL NRNPFHQKQP VSAMEYEKIL MDIGGLSRAQ ILLFVLLSFT
NLKSCLEFQL LALFMHQPKF LCGQAAGNDT GWSVSEDQCT VTAAGGNGTR ACSSFVYPVE
PGAPLSGSNL VSRYDLVCDR AYLRDLLPPV YFAGTAVGMV FGTLGDRLGR KTIILCFLLL
DAVSSPLPAL APNMALQLAS RFVKGISSAV YYQSLLLVEE LTAERYRSLL GNLFWLFWCA
GYMTSGALVA VIGDWRLVQF ATLAPCLVYI AIAWAVPESP RWLVLRGRQA EAVAVFRRLA
SWNGIRLAPD YFAPGGGGGG GGGGAEADEP GELELVVVEK EPTGRLAELF IYPEMRKKTL
VVFFMLTAFS FTYYGLSADV EFTTSNVVLN QVYTGLVEIP SSFIGWLLSD YLGRRWPTLA
MTLVSGVGVV LVPHVPKATL AGLRTGIALF AKCILTAAYC IMDLYATELL PTSVRNNGLF
LATFLATVGN IVAPYTNSLA RHGHYLPGLV FGGLTVASSL SLLLLPETRG LPLPETVASA
EGMRRGTEAA WLAEQRRLRR DEVAANGDKA AVSDGEGEAA IRLTAKSV
//
