ID A0A267G044_9PLAT Unreviewed; 627 AA.
AC A0A267G044;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 22-FEB-2023, entry version 17.
DE RecName: Full=UDENN domain-containing protein {ECO:0000259|PROSITE:PS50211};
DE Flags: Fragment;
GN ORFNames=BOX15_Mlig022099g1 {ECO:0000313|EMBL:PAA78804.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA78804.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA78804.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA78804.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA78804.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA78804.1}.
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DR EMBL; NIVC01000666; PAA78804.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267G044; -.
DR STRING; 282301.A0A267G044; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR Gene3D; 3.40.50.11500; -; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR040032; DENND1A/B/C.
DR InterPro; IPR037516; Tripartite_DENN.
DR PANTHER; PTHR13196; DENN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR13196:SF14; UDENN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR PROSITE; PS50211; DENN; 1.
PE 4: Predicted;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 28..391
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT REGION 435..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 501..523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..470
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PAA78804.1"
SQ SEQUENCE 627 AA; 67715 MW; 54E129C8CF4884B3 CRC64;
AVTAKSASPM KQGIHSRLLP PESGASAFEA LYRLRRRLCG GQTSVVAASS TADDWRLRVV
EYALPDCCDS RGSDWQPEDG DTLCTAFTDI NSRFTFLFAV FTRLHVGEDY IVECLALVTR
RPGFDIFPAL LRQLSGQWPV DPVLAISQQL ATSVTMGQPT GHRDSQLPDT GQWGPARELS
DRLGRCSDTL LYLLTAMLTE RKLLLVARRL DRLTLCAFGC VSMLYPFSWE HVFAPSLSAA
NIDHIGCLVP CVFGLVEALY VTNRAKVDAN FADRDFALVN LDSGDLFVAD GAEASAEQLG
LPKRLVRAAK RSLSRSRSSS APGDAFSQAL LRVTVELLAP IRQQPAGSDF NLDAFLAASP
ESHRAFLRRL SGSQLFREFV DRYLAAGTSE SHYEAFNRAA DRLLASRQRK RAIVNLPRNI
GRRVRSNLLS RRLASAHSAA QQLPQKPELI GEKLESDDDA EEDEAEEGFD EADGVVKSLN
DSLAPTVMLN SGVGDDVGEG SGEGVLINID DSDSGSNNND AASLHSAASS LHSIGGPAHV
HFVSPPSTLP LRPQQAQTDS IEDWSALIGD SRPAPAPESS SETDLLQFSS PLKAQILSRY
GTGASRPASF PIGSAATGMG NNWVSFA
//
