ID A0A267G0S2_9PLAT Unreviewed; 356 AA.
AC A0A267G0S2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=ETS domain-containing protein {ECO:0000259|PROSITE:PS50061};
GN ORFNames=BOX15_Mlig020521g1 {ECO:0000313|EMBL:PAA79631.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA79631.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA79631.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA79631.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA79631.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA79631.1}.
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DR EMBL; NIVC01000623; PAA79631.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267G0S2; -.
DR STRING; 282301.A0A267G0S2; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 234..298
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 62..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..87
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 40013 MW; 9BF39F7623388882 CRC64;
MMAAGLPNDV SVVDYLGYDP ALPLPRDIEA VGNINLDDLN GLVENVDLEA QQVFILPQQL
QDSPDQVSVM PPPPPPPPPP PPLWPPHVAG SLSMTHHPAP PASQQQRAEI PKQLRDRVEK
TSEAIQLPVH TISSWSSHQK LKWIKAMVTR HLPNPSVQQH QRLFNLGNEL SQSDRRSLEE
LIQLVEQAAQ DPSIGRKLTA ELNGWRRVCE VHLVELRSIK PEPKPGTHGR GTGDYLWEHV
LRLLMEGSPT VAWLNREEGL FVFKDSSGAA RSWGYTKNNV NMSFEKMSRS IRQYYRPDGT
GIIEKAPEQP KLHYKFNMFH PEVASFLAKN FRAICERHAF LSRVVHGAPV GSENLC
//
