ID A0A267G0V7_9PLAT Unreviewed; 465 AA.
AC A0A267G0V7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 13-SEP-2023, entry version 17.
DE RecName: Full=DNA polymerase delta subunit 2 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=BOX15_Mlig013796g2 {ECO:0000313|EMBL:PAA79671.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA79671.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA79671.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA79671.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA79671.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA polymerase delta/II small subunit
CC family. {ECO:0000256|ARBA:ARBA00006035}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA79671.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NIVC01000621; PAA79671.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267G0V7; -.
DR STRING; 282301.A0A267G0V7; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0043625; C:delta DNA polymerase complex; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd07387; MPP_PolD2_C; 1.
DR Gene3D; 2.40.50.430; -; 1.
DR Gene3D; 3.60.21.50; -; 1.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR040663; DNA_pol_D_N.
DR InterPro; IPR024826; DNA_pol_delta/II_ssu.
DR InterPro; IPR041863; PolD2_C.
DR PANTHER; PTHR10416; DNA POLYMERASE DELTA SUBUNIT 2; 1.
DR PANTHER; PTHR10416:SF0; DNA POLYMERASE DELTA SUBUNIT 2; 1.
DR Pfam; PF18018; DNA_pol_D_N; 1.
DR Pfam; PF04042; DNA_pol_E_B; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 36..163
FT /note="DNA polymerase delta subunit OB-fold"
FT /evidence="ECO:0000259|Pfam:PF18018"
FT DOMAIN 189..403
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PAA79671.1"
SQ SEQUENCE 465 AA; 51628 MW; 4F6FC7F822C99E21 CRC64;
YTAAMPAELL QRLIAPYENL SSDYVIPAGN RNYRLQYSHV YSQRLHSMRA QLEALARERW
PSLPLRRISE IVTGERCIVV GTLFKDMPLK PSILSEIGED QQVEPPPVPE CCVSDKDRLI
LEDDLQRIQL VGDIAKERLV TGIVLAVLGK EPDEARGRFQ VEEHLFAQPA PQPQWLPLEP
EPEQDIWLAV VSGLHLGDPA EDVLRLRLLV QRLTCSLIPS DSMRQSAASV VRLLIAGNSL
AKSTQDQESH SRALYLSKKA AVTSAAGVSR LDSLVSELAA SIPVDLMPGE FDPSGYFLPQ
QPLHHCMLPQ SGRYSSLNLV TNPYRFRLAD WHILATSGQT VKDVKKFSNI RDPLDLMEGT
LRWRHLAPTA PDTLGCFPFY ESDPLLLDFS PHLYIAGNQA SFGHRLVKDA AGQETLLVSV
PAFADTGECA LVGLRSRRVR RLLLSAEGFH GAGRRADAEV PMDTD
//
