ID   A0A267G1R0_9PLAT        Unreviewed;       505 AA.
AC   A0A267G1R0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   RecName: Full=Ammonium transporter AmtB-like domain-containing protein {ECO:0000259|Pfam:PF00909};
DE   Flags: Fragment;
GN   ORFNames=BOX15_Mlig015994g3 {ECO:0000313|EMBL:PAA79384.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA79384.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA79384.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA79384.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA79384.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ammonium transporter (TC 2.A.49) family. Rh
CC       subfamily. {ECO:0000256|ARBA:ARBA00011036}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA79384.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NIVC01000637; PAA79384.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267G1R0; -.
DR   STRING; 282301.A0A267G1R0; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR   InterPro; IPR029020; Ammonium/urea_transptr.
DR   InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR   InterPro; IPR002229; RhesusRHD.
DR   PANTHER; PTHR11730; AMMONIUM TRANSPORTER; 1.
DR   PANTHER; PTHR11730:SF60; RH50, ISOFORM D; 1.
DR   Pfam; PF00909; Ammonium_transp; 1.
DR   PRINTS; PR00342; RHESUSRHD.
DR   SUPFAM; SSF111352; Ammonium transporter; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        33..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        91..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        149..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        175..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        236..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        275..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        328..345
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        366..384
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        432..457
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          77..461
FT                   /note="Ammonium transporter AmtB-like"
FT                   /evidence="ECO:0000259|Pfam:PF00909"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:PAA79384.1"
SQ   SEQUENCE   505 AA;  53348 MW;  6DF1C0C53A5BCBC6 CRC64;
     SLLPVQFCKP AFAFLPQSPG SAAATMEFGN AKFGAVALAL QALFVALFAA FAKYDEQADA
     GLWGNATGRL RPAEVGTENS LGPNYPMFQD VHVMIFAGFG FLMTFLKWYG FCSVGLNMLI
     SALVIQWGML VNGFFHLKDA KFSIDIQGLL AADFACAAVL ISFGAMLGRL SPLQCLVLSL
     VEIPIFVANE YVGLYIFKAA DMGGSMFVHV FGAYFGIAAS KALTAPGDGK NSNDHSGYSS
     DLFAMIGTIF LWLYWPSFNA GLASGDDKHR AVINTYLSLA ACTVVAYAAS ALFEKGKFEM
     SHIQNATLAG GVAVGTVADM MIRPYGALII GCLAGLLSVF GYAVIAKKLR AANILDTCGV
     NNLHGMPGLL AGLLGIIYSA SASLDDYGNG LYQIFPARAP VTANGSAFEY VVKDGTLSVE
     GGGAGRSAGS QAAFQAAALG LTLLCAVLGG LLTGFILRLP ILDPVRMENF FQDDRFWHVP
     SNYDARPFGG EGSVPLNDKE AEEPV
//