ID A0A267G2C8_9PLAT Unreviewed; 526 AA.
AC A0A267G2C8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=G-protein coupled receptors family 1 profile domain-containing protein {ECO:0000259|PROSITE:PS50262};
GN ORFNames=BOX15_Mlig010372g1 {ECO:0000313|EMBL:PAA79564.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA79564.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA79564.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA79564.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA79564.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA79564.1}.
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DR EMBL; NIVC01000628; PAA79564.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267G2C8; -.
DR STRING; 282301.A0A267G2C8; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004983; F:neuropeptide Y receptor activity; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000611; NPY_rcpt.
DR PANTHER; PTHR24235:SF29; GH23382P; 1.
DR PANTHER; PTHR24235; NEUROPEPTIDE Y RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR01012; NRPEPTIDEYR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|RuleBase:RU000688};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Transducer {ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 106..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 125..416
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 503..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 526 AA; 58137 MW; 74303D2D065D45E3 CRC64;
MVLLGEAVRE ICRQGLFCKM TSGELMSTRE ERTLTVQHPI VLMAHCLWCG SSAINEASSC
FSHILSNLNS SGPVSQLSHP SSKSTQQPQL QQSNLSHLDD GVKVTAAVGV AVALHCLLIA
VGLVSNLLVS GMLIRRRQFA NVTNLFVLGL SLSDILICGL LMPSLMYYDL SRRGYISASP
PGRLYCQLLL TSLNVPIYAS CLIILWIAVD RHRLICQPHR RRMSRPVAVG LLLLTGLVSA
LVHSPTVAFN APPDGRRSQF CAEQWPDKRL RLAYSIGAFC LQFCTPLLVT GALYSRIYRR
LQVRAANRQR RETRRKRRTN RILVAIVISF AIFWSPWSVF NVVSEIEQFK RRADPVEVAA
FLDCVNMTQP WDTVNENLRT LFDSYTDSIV QGSWNLLELY VRLFALGSAC VNPYLYGWLN
EQVRSGLTAC LPCCAGPRGF DAEGSGSRYR GESRSDFRST RRGFLASSCR SATRQMSLQP
MRPASSAAGS VVGGNGHRGS LNTDCSGAVG KRKNRQPVSV VMETAA
//
