ID A0A267G478_9PLAT Unreviewed; 622 AA.
AC A0A267G478;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=BOX15_Mlig020596g2 {ECO:0000313|EMBL:PAA80840.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA80840.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA80840.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA80840.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA80840.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA80840.1}.
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DR EMBL; NIVC01000563; PAA80840.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267G478; -.
DR STRING; 282301.A0A267G478; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24114; LEUCINE RICH REPEAT FAMILY PROTEIN; 1.
DR PANTHER; PTHR24114:SF2; PH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13516; LRR_6; 5.
DR SMART; SM00368; LRR_RI; 7.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 541..576
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..65
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..105
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 622 AA; 67491 MW; C2A46F55DACAE684 CRC64;
MSATDSVDDL VQDSGLEAAP GEGPSGLVGM EEAAEAEAEA PADERATFLT EARTADREHG
GSAVEEHAES SAAADEEENE AGELHELDTI REDTTMEKAE EAADVAAENA DEAEADEAVD
GEAAAAATEA PPPAESSKSR PSSRRSSKPP PGSAGRVRRE RTIESLLDND ELWDTDLEDE
LPEEGHAADL HDTTGRSLYR TTCERLGAVP VKYFLKHLTD TRLIMRHHGL GPVGTRAIAR
PLAINLTITE LDLTGNWMEP EGGRAIAKML EENSYITHLW LADNKLCDEG AAQICRVLQT
NSASVTHLSL AGNEIGDQAA DSLFDLLANN RTLVSLNLSR NCLGGEAAAR LGAGLGINDY
LEELDLSGNR ISGPGAVELA QGIRESFRLK KCNLAWNGFA EEGGRALADM LKANQALQEL
NIEGNRLNGN AAVAIGNAVA GNEILLELRM GNNFLYTAEL LQVVKLIVAS ETTPLTFLSF
KDIPVDYEFV KTVEQQMRRT TRDFQCEHGP VLRAGNTRDE LAKPAIDIRS PIVLLREHIL
INDFRFVERL AAMDAQGNGT VSLEQFAAVM DEMKIPYYRS QLSDLVAKLD KLGDGSIYYA
DFMPPERPRR ESAMIRSRGA MT
//
