ID A0A267G8J5_9PLAT Unreviewed; 561 AA.
AC A0A267G8J5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 22-FEB-2023, entry version 17.
DE RecName: Full=NUC153 domain-containing protein {ECO:0000259|Pfam:PF08159};
GN ORFNames=BOX15_Mlig002698g2 {ECO:0000313|EMBL:PAA82306.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA82306.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA82306.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA82306.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA82306.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the ESF1 family.
CC {ECO:0000256|ARBA:ARBA00009087}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA82306.1}.
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DR EMBL; NIVC01000481; PAA82306.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267G8J5; -.
DR STRING; 282301.A0A267G8J5; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR InterPro; IPR039754; Esf1.
DR InterPro; IPR012580; NUC153.
DR PANTHER; PTHR12202:SF0; ESF1 HOMOLOG; 1.
DR PANTHER; PTHR12202; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 519..539
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 1..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 385..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 419..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..102
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..126
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 61986 MW; 7CE5B485412531C9 CRC64;
MFTDPEFSTS VRSDKRGRPV AMSSRQDLSR FYGLKQGRHG EDEDDNDEVE ASSDNQEDQE
SEDAVDKDED EEDEEVAEEE SDSDEEDDDD DEQNEADNDE EGSDSEARSS SDEEFRNLER
SSSAAIDEEN DQSVVPTNRL AVTQQDWEQI KATDLFMLLS SHCPSSVGRL LSVTVYPSKF
GQHRMAEEAK VGPLELRRKA LSDPAKKSST SSGSYRRSLR RYQLKRLWYY YAVAEFDCTP
AATSVYEQCS GLEVESTGGC LRLSYVPAGM EFGGPDDVPD EWRHLVTRCT GLDPAAYKPR
KLTAGLLNRT KVGLTWDETP TERTRYLQGL FNKTDFNEDD PDLNRLSEFL NLSSDESDND
EEDSDAIKAR TAKLRRALLG DDVGADKAED NADNGSELPA TFSDDELPDD IALAMQDVDA
KAKSSAKGQK QQEQSEPKES RKRTRRRRLK EQAKRAKLAK AGLLPSKADG AGGSGDSDEG
DSGEGEGEMP ASEQELAMLV ADRVAGAHST VTAADVAADE RFGALFTDPN YHVDPTHSEA
SKAVEVQKLI VGAKRKRAAF D
//
