ID A0A267G978_9PLAT Unreviewed; 479 AA.
AC A0A267G978;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 13-SEP-2023, entry version 14.
DE RecName: Full=START domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BOX15_Mlig006454g1 {ECO:0000313|EMBL:PAA82603.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA82603.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA82603.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA82603.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA82603.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA82603.1}.
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DR EMBL; NIVC01000461; PAA82603.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267G978; -.
DR STRING; 282301.A0A267G978; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR Gene3D; 3.30.530.20; -; 1.
DR InterPro; IPR019498; MENTAL.
DR InterPro; IPR000799; StAR-like.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR PANTHER; PTHR46121; STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE; 1.
DR PANTHER; PTHR46121:SF4; STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE; 1.
DR Pfam; PF10457; MENTAL; 1.
DR Pfam; PF01852; START; 1.
DR PRINTS; PR00978; STARPROTEIN.
DR SMART; SM00234; START; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR PROSITE; PS51439; MENTAL; 1.
DR PROSITE; PS50848; START; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 62..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 56..230
FT /note="MENTAL"
FT /evidence="ECO:0000259|PROSITE:PS51439"
FT DOMAIN 276..471
FT /note="START"
FT /evidence="ECO:0000259|PROSITE:PS50848"
SQ SEQUENCE 479 AA; 52801 MW; 411701E2BE8F2833 CRC64;
MQSSATAVTD FQLPASSAGL SVNAVTVDEV HAPSSNSATG MEATAASVDS GRHSKIGTLR
RAFCLLVLFD LIFTCILWIF YTKYLGLDLG KAIRDQVLHY QFTSSVFDLV GVSLVRFILL
EVFYAALRLQ SPWVVAVTTA FSTAFIIVKI ILYDYDHGHS VFDYLLPIMS LVLVWIETFL
LDCKVLPKER ADEQLNERSP LLSGGRSSSV TAEYVYRGGL RHSFVPSEGF VTPQSSPNNS
DNEDDGAAAN SQVAASSLLS IEERHRLALR ASRLADESWQ ALEDAGWRCV HDRPPVRVLS
QRSRHRPSGK AWRLETRLPI SADRAFREIW DRVDRQADWN PTVQFSRLLL RLDSDTAIVH
NATAEAGGGL IKARDFVTLC VRRSRENGIR YTGGVSIETG LMPKMDGYTR GENHPGCIAC
IPDGPGACQL VWIVDSDIKG WVPTRVIDQA MTSVMTQLGA SLQSHASRIA QKEGLSPAM
//
