ID   A0A267GIA0_9PLAT        Unreviewed;       688 AA.
AC   A0A267GIA0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=Carboxylesterase type B domain-containing protein {ECO:0000259|Pfam:PF00135};
GN   ORFNames=BOX15_Mlig005467g2 {ECO:0000313|EMBL:PAA85785.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA85785.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA85785.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA85785.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA85785.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA85785.1}.
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DR   EMBL; NIVC01000304; PAA85785.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267GIA0; -.
DR   STRING; 282301.A0A267GIA0; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019819; Carboxylesterase_B_CS.
DR   PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR   PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR   Pfam; PF00135; COesterase; 2.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 2.
DR   PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..688
FT                   /note="Carboxylesterase type B domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012311906"
FT   DOMAIN          55..485
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
FT   DOMAIN          569..653
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
FT   REGION          525..550
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        529..548
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   688 AA;  72789 MW;  2657CABB75E5C133 CRC64;
     MYRAAIATLA VVALTLTAAR GQPQPVGEAN VTIGSCSIVG SEFNLTMPDG LGSRLLRFLR
     VPYAEPPIGD RRLAKPQPFN FSRSDCRLTG EEAADPEENL LRLSIRTPDL APADPLPVLA
     LLLDGSSDFN DSLGHEVGDA IGTNVVMATI GSRFGVLGNV PAGQNNGLED QRLALEFLRD
     QLHRFGGDPA RVTLAGHGAA AAAVGLHAVG SGGFSRVVMM SGSIAAPLGW SASAEVAAAL
     DRQLAASLSC GIGDEGRLPL DCLRSKPLKD LLDAESLLRR DYGDGAGRFA PSFNVSLLPD
     ALWRSGAFNG SLMVGVGTGV GPALAELALR VQGADWGALD QTAFETILDR EFGQFPRLHS
     AGRNASVSGR RYLRLTLSDW PHFAYGGRVR HILARALSDF GAVCPVWEAA NDLIGSGRVF
     VYLHDEDGDP AAALSVANDA KVLLGEPLVR ANYSAEHRSL SRIMMQHLVD FTASGAPSPG
     WPSSSAGAFD FLRFGAKTGV NSTSGGFAFE PGRCPLWSAE MSLASNLSAS PPPPQPPLPP
     PPPRISPGGA QPFSNTVLRN YTVNILGLGL TFGQTIRTPA GKVMTQFLGL PYAKPPIEGK
     RFAVPEPADP FGEDFLAISP KPACPQPGPL ATSEDCLYLN LWTPRTRTGK SKTSPSWCSF
     TAASFRLATP SMSAGGAATC WTRWMRWW
//