ID   A0A267GKW4_9PLAT        Unreviewed;       531 AA.
AC   A0A267GKW4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PAA86658.1};
GN   ORFNames=BOX15_Mlig026950g1 {ECO:0000313|EMBL:PAA86658.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA86658.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA86658.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA86658.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA86658.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the bile acid:sodium symporter (BASS) (TC
CC       2.A.28) family. {ECO:0000256|ARBA:ARBA00006528}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA86658.1}.
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DR   EMBL; NIVC01000269; PAA86658.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267GKW4; -.
DR   STRING; 282301.A0A267GKW4; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR   InterPro; IPR004710; Bilac:Na_transpt.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   PANTHER; PTHR10361:SF28; RH04535P; 1.
DR   PANTHER; PTHR10361; SODIUM-BILE ACID COTRANSPORTER; 1.
DR   Pfam; PF01758; SBF; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Signal {ECO:0000256|SAM:SignalP}; Symport {ECO:0000256|ARBA:ARBA00022847};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022847}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..531
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012740848"
FT   TRANSMEM        202..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        233..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        262..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        297..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        327..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        363..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        394..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        421..438
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        450..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   531 AA;  57292 MW;  0D1DFDF97E07CE60 CRC64;
     MPIKLPLLHL LLLLRLGAAA EAVSPPFINA TIAACEVSVS PSVVEAQTVG TYQSLTVNCS
     CCDSIAEAGW LVAVRASISN AQIAAITAMN RRERQAIPVQ AALRRRCDVG EACTFREFPY
     SAGEVKQLYI EANNVGRARI LISLFAVNSS SWAQLKSVVR KPAAQPGADS EDSLPNKVPL
     GSGEISIVAL RKQRMIDRAF EWSIGLVASV LAFCMGCMTD LRETRPHYKR PLALLTCLIL
     QHLFLPPIAL GLYKLFGIAD DMGFGLVAIA TMPGGGMAHL TVFLMSGDRN LSAAISLLNA
     LINLGLSPAW LSLFTHYLQF ELLHYRLVLW LLMLFISQFI GSLVATCRPG LAQAALNWVG
     RPLLLLATIL MVTLGIYINH YAIDHLESKE MGCVLAFIAS GFCLGGLASY LVKLDKPRRK
     TLAAETACCA CLVAIPAIRM SCDSPTADLA TIMPLAAAIF TPAPIIVYLV SHRVKGLLGS
     FIDKRKEKQS RHYSIVSSLA KMAEDVTAVS APLVIEEGED GSAEKQKVTT L
//