ID A0A267GUI6_9PLAT Unreviewed; 668 AA.
AC A0A267GUI6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=BTB domain-containing protein {ECO:0000259|SMART:SM00225};
GN ORFNames=BOX15_Mlig002764g1 {ECO:0000313|EMBL:PAA89685.1},
GN BOX15_Mlig002764g3 {ECO:0000313|EMBL:PAA75403.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA89685.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA89685.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA89685.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA89685.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA89685.1}.
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DR EMBL; NIVC01000887; PAA75403.1; -; Genomic_DNA.
DR EMBL; NIVC01000142; PAA89685.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267GUI6; -.
DR STRING; 282301.A0A267GUI6; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003974; K_chnl_volt-dep_Kv3.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF252; POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAW; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR PRINTS; PR01498; SHAWCHANNEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 168..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..114
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 525..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 599..668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 633..648
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 668 AA; 74294 MW; 68EC15FBEB792D75 CRC64;
MAAESVEGDR TRVVINISGS RFETSYGVLE RFPGTRLSLL ATLRQDDEAY DVDRGEYYFE
RHPEVFADIL HFYRTDELHI RHNLCGNVVK REFEFWGMYE QDIEPCCWTS YSQAAECKET
LAGIDNTFLT GKAAQKESWE AETNGWIKFR RKVWAILEDP STSMASRVYV FTSMLLVVIS
IVCFVAETYE GFRVPIGNAS KVPAANCAMP CGSYVDPQHV PGTLNYNYDE TEPHPVLINI
DYALYALFVI EFIVRVFFAP SFRAYFTDFL NWIDIICVLT HTVSVVMNSL ESLDYSSPLV
KTAMNLRLLR GLRIVRILRI FKLVKHYNAF KILVYTIKIS LRELMLMIVF LFVGAVIFGS
IIHLVERESF KNIPLGLWWA LVTMTTVGYG DFVPRQAAGY AIGCICVIFG VLTIAFTVPI
VVNNFAMYYS HAQSRNKKPK EYWRIKRVPQ KDLKKPTGIM AALSKFKKAP GDAPVPDSSD
LYGGGGGDGA AGKTVSVNSV AMSVMWNNLN LSDAKKSAYQ TDKVTLMTPR GGGDQSGGGG
GGQTTEDSST LTAFAAPTGP RFFARRAPMT PVQEVLDLDM DEARVNEEHE ERSRQLLAQA
QENDQQVSAA KERQADALEK RKAALKSRLA SAKQPQGGAN SSASSDGKKP ASAKKPFPAN
PARPGSKK
//
