ID   A0A267GYQ5_9PLAT        Unreviewed;       457 AA.
AC   A0A267GYQ5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=JmjC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BOX15_Mlig014381g1 {ECO:0000313|EMBL:PAA90419.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA90419.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA90419.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA90419.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA90419.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA90419.1}.
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DR   EMBL; NIVC01000110; PAA90419.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267GYQ5; -.
DR   STRING; 282301.A0A267GYQ5; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   Gene3D; 2.60.120.650; Cupin; 1.
DR   InterPro; IPR041667; Cupin_8.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR003347; JmjC_dom.
DR   PANTHER; PTHR12461; HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED; 1.
DR   PANTHER; PTHR12461:SF18; JMJC DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13621; Cupin_8; 1.
DR   SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
DR   PROSITE; PS51184; JMJC; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..457
FT                   /note="JmjC domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011995173"
FT   DOMAIN          132..296
FT                   /note="JmjC"
FT                   /evidence="ECO:0000259|PROSITE:PS51184"
FT   DOMAIN          354..389
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          26..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   457 AA;  51337 MW;  8B6202B60543D739 CRC64;
     MLHRFVVALL PLLLLLPLLV ASSESPSEDA TASNDEGHLK PFGQQGPLHP IDSVDGFIPP
     EEFLTNYVQA NRPLLFRGGA KVSPAFEKWT DAYLSENTPP RPAGDVFIEH NKKENRSQRY
     SFIHFKKFLS IYNTSDIYMV SEVPSFLLKD LVVPFPLQCK YFVQGGLDTH VAWFSSGGTS
     SVIHYDDYEN VNCLLRGRKT LVFLNTTRYA SQVNSIIDKD DRGYSSADSD AINVKARPEF
     SGLEFHLAEM QAGDCLYIPN YWVHQVRSFD NNLAVNLWWT KRDSYDTSGC GKIIDPDLRF
     SRVLFAARLK AARDDAYSIR QALASNLKLP VTQLEFLDFL SRGDTQSLSS SFPDFPPAAA
     ALFQSLDVNK DGALTEEEFK GKMKLKTGRE IKAAATAYNV QVFAMHEAAD EKDVSRLPKL
     LATSDSGEEV FTPERTWLTE EQRKSIEVAE KSSKDEL
//