ID A0A267H212_9PLAT Unreviewed; 629 AA.
AC A0A267H212;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=BTB domain-containing protein {ECO:0000259|SMART:SM00225};
GN ORFNames=BOX15_Mlig018250g2 {ECO:0000313|EMBL:PAA92340.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA92340.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA92340.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA92340.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA92340.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, dendrite
CC {ECO:0000256|ARBA:ARBA00004279}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA92340.1}.
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DR EMBL; NIVC01000056; PAA92340.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267H212; -.
DR STRING; 282301.A0A267H212; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003975; K_chnl_volt-dep_Kv4.
DR InterPro; IPR024587; K_chnl_volt-dep_Kv4_C.
DR InterPro; IPR021645; Shal-type_N.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF105; POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAL; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF11879; DUF3399; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF11601; Shal-type; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR PRINTS; PR01497; SHALCHANNEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 227..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..144
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
SQ SEQUENCE 629 AA; 68290 MW; D09E54602DF26267 CRC64;
MAAVAAWLPF ARAAAIGWVP VAQHPMPRPP PPSVQHSPGE HRSDEKLSII VSGRLFVTWR
NTLEKFPNTL LGSDEKEYFL DESTGQYFFD RDPDMFRHIL TYYRTGKLHF PRSECIADYE
EELAFFGIAP DVMGDCCFED YRDRKRENAE RLFEDKDSEA EKCMPHSNVR EKLWRGFENP
QSSTAALVFY YVTGFFIAVS VLANVIETIP CGIVPGTNLN PACGDKFSNA FFCLDTACVL
IFTMEYLARL YAAPDRLKHA REVMSVIDLV AILPYYIGLF MPDNKDLSGA FVTLRVFRVF
RIFKFSRHSM GLRILGYTLQ SCASELGFLL FSMSMAVIIF ATVMYYAEKN QPDTGFSSIP
ASFWYTIVTM TTLGYGDIVP ATIMGKIVGG VCSLSGVLVI ALPVPVIVSN FSRIYHQNQR
ADKRKAEKKS RLARIRLVKA TSGAAFIASK LRCSGSADAA ALAAASGASD EHLAGNHSAA
ASAASNAVAA ATSAAVAGPF ERQHYHLLTC LERTTGREFA DVDQADLQSL QWDLKIQEKS
TAQSPSTHAA DDDAEVAVAS GEPGTVSGCC GILGLGLSCN TDGTKQLSGR SSPAEEAAGI
ESISLKAHHL VDETGAPAAA ATSGTSAAV
//
