ID   A0A267H372_9PLAT        Unreviewed;       311 AA.
AC   A0A267H372;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN   ORFNames=BOX15_Mlig019668g1 {ECO:0000313|EMBL:PAA91992.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA91992.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA91992.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA91992.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA91992.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Ligand for members of the frizzled family of seven
CC       transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC   -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC       ECO:0000256|RuleBase:RU003500}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA91992.1}.
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DR   EMBL; NIVC01000067; PAA91992.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267H372; -.
DR   STRING; 282301.A0A267H372; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR005817; Wnt.
DR   PANTHER; PTHR12027; WNT RELATED; 1.
DR   Pfam; PF00110; wnt; 1.
DR   PRINTS; PR01349; WNTPROTEIN.
DR   SMART; SM00097; WNT1; 1.
PE   3: Inferred from homology;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW   ECO:0000256|RuleBase:RU003500};
KW   Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW   ECO:0000256|RuleBase:RU003500}.
SQ   SEQUENCE   311 AA;  35570 MW;  F813FC610ABC5CC1 CRC64;
     MSGFVLATTL ANDCARGVIA NCPCGAEPRW LRARWPEVRF SLEGCHTNLR MGQRLARQFL
     GFAGKRKRAR RRRPRGRRTV KTFDRFVKKV NRHNYRVGIR ATKHSEAVRC KCHGSSASCT
     IRTCHKVLHQ RGIQMIPSAY VRRYEDDPID FLINLYDKQN LRRTIFDERG YQGYEERCTE
     ADRQAGSNPL AAKPLCESYK VVPGLPRASV LLFKEHSLDY CSRREDVYPG TSNRECLPDG
     SPEAQQILAS DTGERRREIL CSVMCCGRPY RNVTVSYPGN HPDCKAKSCR LLQNPFRVDC
     QPCVLSKSFC S
//