ID A0A267H4A2_9PLAT Unreviewed; 982 AA.
AC A0A267H4A2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Coatomer subunit beta {ECO:0000256|ARBA:ARBA00017024};
DE AltName: Full=Beta-coat protein {ECO:0000256|ARBA:ARBA00030841};
DE Flags: Fragment;
GN ORFNames=BOX15_Mlig004513g4 {ECO:0000313|EMBL:PAA92524.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA92524.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA92524.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA92524.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA92524.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPI-coated vesicle membrane
CC {ECO:0000256|ARBA:ARBA00004347}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004347}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004347}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004255}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004255}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004255}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA92524.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NIVC01000049; PAA92524.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267H4A2; -.
DR STRING; 282301.A0A267H4A2; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0030126; C:COPI vesicle coat; IEA:InterPro.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR011710; Coatomer_bsu_C.
DR InterPro; IPR016460; COPB1.
DR InterPro; IPR029446; COPB1_appendage_platform_dom.
DR PANTHER; PTHR10635; COATOMER SUBUNIT BETA; 1.
DR PANTHER; PTHR10635:SF0; COATOMER SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF07718; Coatamer_beta_C; 1.
DR Pfam; PF14806; Coatomer_b_Cpla; 1.
DR PIRSF; PIRSF005727; Coatomer_beta_subunit; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 21..502
FT /note="Clathrin/coatomer adaptor adaptin-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01602"
FT DOMAIN 693..832
FT /note="Coatomer beta subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07718"
FT DOMAIN 839..969
FT /note="Coatomer beta subunit appendage platform"
FT /evidence="ECO:0000259|Pfam:PF14806"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 501..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..521
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PAA92524.1"
SQ SEQUENCE 982 AA; 109179 MW; D2DC1A13BE78E111 CRC64;
SQAEQPCYTL INMPTDSEPP SEQKLREDLE KPDVNGKIEA LKKVIAMIIN GEKFNSSLLM
TVVKYVMPSQ DHMIKKLLLV FWEVVPKYSP DGKLLHEMIL VCDAYRKDLQ HPNEFIRGST
LRFLCKLKEP ELLEPLMPSI RQCLEYRHTY VRRNAILAIF TIYKNFDSLI PDAPELIASL
LDQEQDASCK RNAFMMLLHV DQERALNYLS TCLDQVHTFG DILQLVIVEL IYKVCHANPT
ERSRFIRCVY NLLQSSSAAV RYEAAGTLIC LSSAPTAVRS AASAYIDLIL KESDNNVKLI
VLDRLVGLRE THERILQDLV MDVLRILSAT DLEVRKKAMD LALELVTGRT IEEVVGVLKK
EVLKTSAAIE QEETGRYRQL LVRTLHNACI RFPDVAPQIV PTLIEFLADG DNYNEKAPTG
AAEDVLVFVR EAIQKFDHLK SLILQKLMES LATVKNAKIY RSALWILGEH CTEVEDIQSV
MTLVCQALGD LPLVEDELKR AASTGEDQDQ QQESALSSQA SGLAQKRVTA DGTYASQTAF
SVTGGKSGSS GGKSGGVGAS LGTDKDDRPV LRRHLLKGDF FIGAALGTAL TKLAVRYLAR
VPDPTRQNRF VAECMLVLSC ILHLGRSGMP ERPVSPDDFE HLWLCMKVLA ERSQPMMEVF
DLYCREALDQ LLSSQLAEEK SCETVRTKRA VQPDDPVRFI QLAPANEFGD LEDRFDLTLS
QALGTAAKPE SDILLSSKLN KVTQLTGFSD PVYAEAYVHV NQYDIVLDVL LVNQTADTLQ
SLSLELATLG DLKLVEKPAP LTLASKDFAN IKANIKVTST ENGIIFGNIV YDVRGAAGDR
NCVVLNDIHI DIMDYIVPSH CSDVDFRRMW VEFEWENKVA VATGISDLRD FLAHLIKATN
MRCLTPEKAL TGECGFLAAN LYARSIFGED ALANLSIEKP PNQPNAPVTG HIRIRAKSQG
MAVTLGDKIN MSQKQTLRAP AS
//
