ID A0A268E4R8_9BACI Unreviewed; 299 AA.
AC A0A268E4R8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Flap endonuclease {ECO:0000313|EMBL:PAD68102.1};
GN ORFNames=CHH83_15505 {ECO:0000313|EMBL:PAD68102.1};
OS Bacillus sp. 7586-K.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=2021690 {ECO:0000313|EMBL:PAD68102.1, ECO:0000313|Proteomes:UP000216230};
RN [1] {ECO:0000313|EMBL:PAD68102.1, ECO:0000313|Proteomes:UP000216230}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7586-K {ECO:0000313|EMBL:PAD68102.1,
RC ECO:0000313|Proteomes:UP000216230};
RA Kalinowski J., Ahrens B., Al-Dilaimi A., Winkler A., Wibberg D.,
RA Schleenbecker U., Ruckert C., Wolfel R., Grass G.;
RT "Isolation and whole genome analysis of endospore-forming bacteria from
RT heroin.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAD68102.1}.
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DR EMBL; NPCL01000064; PAD68102.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A268E4R8; -.
DR OrthoDB; 9806424at2; -.
DR Proteomes; UP000216230; Unassembled WGS sequence.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SMART; SM00279; HhH2; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000313|EMBL:PAD68102.1};
KW Hydrolase {ECO:0000313|EMBL:PAD68102.1};
KW Nuclease {ECO:0000313|EMBL:PAD68102.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000216230}.
FT DOMAIN 6..267
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 299 AA; 33725 MW; A3E2ACD7340C9FCD CRC64;
MLKEDNHLLI VDGMALLFRS FFATSVYGNF MVNSKGIPTN AVNGLLKHLI AAIEYVKPSH
VVCCWDMGSK TYRNNIFSNY KANRPEAPIE LQPQFDLAKE VVKALDIPNI GLEGYEADDC
IGTLTKTFEA DMRITILTGD RDILQLLNDQ VNVLIFQKGI GNYKHYTKQL FQQEFEIEPE
MLIDVKALMG DSSDNYPGVK GIGEKTAYKL VSKYKSISSL LDNIDELTKG QRTKIENDLE
MLHLSKQLAE INCQAPIECN LENAQLTINE EKAFSMIEDH ELKGIQNLLK NITSVREAI
//
