ID A0A268E568_9BACI Unreviewed; 364 AA.
AC A0A268E568;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 11.
DE SubName: Full=3-isopropylmalate dehydrogenase {ECO:0000313|EMBL:PAD68237.1};
GN ORFNames=CHH83_14715 {ECO:0000313|EMBL:PAD68237.1};
OS Bacillus sp. 7586-K.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=2021690 {ECO:0000313|EMBL:PAD68237.1, ECO:0000313|Proteomes:UP000216230};
RN [1] {ECO:0000313|EMBL:PAD68237.1, ECO:0000313|Proteomes:UP000216230}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7586-K {ECO:0000313|EMBL:PAD68237.1,
RC ECO:0000313|Proteomes:UP000216230};
RA Kalinowski J., Ahrens B., Al-Dilaimi A., Winkler A., Wibberg D.,
RA Schleenbecker U., Ruckert C., Wolfel R., Grass G.;
RT "Isolation and whole genome analysis of endospore-forming bacteria from
RT heroin.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAD68237.1}.
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DR EMBL; NPCL01000058; PAD68237.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A268E568; -.
DR OrthoDB; 9806254at2; -.
DR Proteomes; UP000216230; Unassembled WGS sequence.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000216230}.
FT DOMAIN 5..353
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 364 AA; 40634 MW; 4CFD1CD47B52B7B4 CRC64;
MPKYKLGILS GDGIGPEIIK SSIKVLNETT RKFTNEIEFE FIELPMGWEG IKKYNDPLPE
ITKKGLEKTN GWLMGPHDSS SYPDEHRISK RNPSGELRHY FDLYSNVRPS RTFPGTTSLV
GKADLIILRE NSEGFLSDRN MYKGVGEYMV TPDIALVTGV FTRKATERIA HVAFKLAMTR
RKKVTIVHKA NVIKLAFELF RDVCYEVGEK YYPEVEIDDF HIDAMTAHLV RRAKDFDVIV
TENLFGDILS DLAGELVGSL GLSPSLNTNG THAMAQAAHG SAPDIAGQNI ANPTSMILST
VMLLHWLSVH HKENKLYELA SIIENAVFRT IAEGTTTYDL GGSASTSEFT EAVINNLKEY
EARM
//
