ID   A0A268E664_9BACI        Unreviewed;       452 AA.
AC   A0A268E664;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=MATE family efflux transporter {ECO:0000313|EMBL:PAD68608.1};
GN   ORFNames=CHH83_13005 {ECO:0000313|EMBL:PAD68608.1};
OS   Bacillus sp. 7586-K.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=2021690 {ECO:0000313|EMBL:PAD68608.1, ECO:0000313|Proteomes:UP000216230};
RN   [1] {ECO:0000313|EMBL:PAD68608.1, ECO:0000313|Proteomes:UP000216230}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=7586-K {ECO:0000313|EMBL:PAD68608.1,
RC   ECO:0000313|Proteomes:UP000216230};
RA   Kalinowski J., Ahrens B., Al-Dilaimi A., Winkler A., Wibberg D.,
RA   Schleenbecker U., Ruckert C., Wolfel R., Grass G.;
RT   "Isolation and whole genome analysis of endospore-forming bacteria from
RT   heroin.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAD68608.1}.
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DR   EMBL; NPCL01000047; PAD68608.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A268E664; -.
DR   OrthoDB; 9806302at2; -.
DR   Proteomes; UP000216230; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR   GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd13134; MATE_like_8; 1.
DR   InterPro; IPR002528; MATE_fam.
DR   InterPro; IPR048279; MdtK-like.
DR   InterPro; IPR047135; YsiQ.
DR   NCBIfam; TIGR00797; matE; 1.
DR   PANTHER; PTHR42925; MULTIDRUG AND TOXIN EFFLUX PROTEIN MATE FAMILY; 1.
DR   PANTHER; PTHR42925:SF1; MULTIDRUG AND TOXIN EFFLUX PROTEIN MATE FAMILY; 1.
DR   Pfam; PF01554; MatE; 2.
DR   PIRSF; PIRSF006603; DinF; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000216230};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        54..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        90..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        131..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        164..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        256..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        281..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        314..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        355..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        385..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        411..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   452 AA;  50106 MW;  532165AB23008436 CRC64;
     MSSEFKNRNL TLFALTWPIF IEQMLHMLMG NADTLMLSQY SDNSVAAVGV SNQILFLLIV
     MFGFIATGTT ILITQYLGAN NVKDAKEVSI VSISANLIIS LILSVAIVIA SDEILRLMNL
     PEELIPEAKS YLQIVGGFSF VQALIMTVSA ILKSYGYTKD TMFLTIGMNL LNVIGNFVLI
     FGAFGIPALG VQGAAISTVV SRIIALFIIF YMLKKRLYFT IKLKDLIHIP MHHLKNLLGI
     GVPTAGEQLS YNTSQMAITF FITMIGTEAL TTRVYTQNLM MFMMLFSIAI SQGTQILIGY
     LIGAKEYESA YKRCLKSLYS GITISILMAV IFSIFSKPLL GIFTSNERIL EVGGLLVLLT
     IILEPGRSFN MVIIGSLRAA GDIKFPTYVG ILSMWGIAVP VAYILGIHFD LGLVGVWIAF
     IADEWFRGII MLYRWKSRAW MTKRFVQKAV TT
//