ID A0A268KB66_9BACI Unreviewed; 691 AA.
AC A0A268KB66;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Sigma-54-dependent Fis family transcriptional regulator {ECO:0000313|EMBL:PAE43888.1};
GN ORFNames=CHI06_04185 {ECO:0000313|EMBL:PAE43888.1};
OS Bacillus sp. 7884-1.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=2021693 {ECO:0000313|EMBL:PAE43888.1, ECO:0000313|Proteomes:UP000216214};
RN [1] {ECO:0000313|EMBL:PAE43888.1, ECO:0000313|Proteomes:UP000216214}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7884-1 {ECO:0000313|EMBL:PAE43888.1,
RC ECO:0000313|Proteomes:UP000216214};
RA Kalinowski J., Ahrens B., Al-Dilaimi A., Winkler A., Wibberg D.,
RA Schleenbecker U., Ruckert C., Wolfel R., Grass G.;
RT "Isolation and whole genome analysis of endospore-forming bacteria from
RT heroin.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAE43888.1}.
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DR EMBL; NPDD01000025; PAE43888.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A268KB66; -.
DR OrthoDB; 9771372at2; -.
DR Proteomes; UP000216214; Unassembled WGS sequence.
DR GO; GO:0008839; F:4-hydroxy-tetrahydrodipicolinate reductase; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0009089; P:lysine biosynthetic process via diaminopimelate; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR000846; DapB_N.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR32071:SF57; SIGMA L-DEPENDENT TRANSCRIPTIONAL REGULATOR YQIR-RELATED; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF01113; DapB_N; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00989; PAS; 2.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50112; PAS; 2.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000216214};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 122..185
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 234..305
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 368..598
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 691 AA; 77356 MW; 8971038D0AC5E8CC CRC64;
MQNVMIVGAG KGGTAVLKLL NETEVLQVKA VIDRNLDAPG IFLAQSLGIK IGIDWKPFLS
ENIDIIIEVT GNEHVFQELR STKDKKTVLI PGSVAFLLAR LLEEKEELIV KHQNASYQQE
LIFNATNDGM LVIDAKGFVI LFNRRAEEMT GVKRDQAIGK YVVEVIPESR LPLILETRRT
ETNQEMVLGN GRKIITTRIP IIEENGTLIG AFAVFKDITE VVNLAEEITD LKEIQTMLQA
IIHSSDDAIS VVDENGRGLL INPAYTRLTG LTQEQVIGQP ATADISEGES MHMKVLQTRR
AVRGVPMRVG ANKREVIVNV APIIVKGKLK GSVGVIHDMS EIKTLNRELN RARQIIRTLE
AKYTFEDIIG SSEEMTLAIE QAKLGAKTPA TVLLRGESGT GKELFAHAIH NASDRKYNKF
IRVNCAAISE SLLESELFGY EEGAFSGAKR GGKRGYFEEA NNGSIFLDEI GELSANTQAK
LLRVLQENEI TRVGGTKPFP INVRIIAATH VNLEKGIAKG SFREDLYYRL NRMPIHIPPL
RNRKEEIPVL CERLIEKINL DYGRNVEGVS QAALLKLVNY DWPGNVRELE NILGRAIIFM
NYYETFINVH HLPELRPKKK SSEPLVTDHS ESIQQDRSLN AMIEDYEAEI IQQTLHRYNG
NKTATAKALG LSVRNLYYKL EKYKIENNSM Q
//
