ID A0A268UC15_9HELI Unreviewed; 642 AA.
AC A0A268UC15;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Formate dehydrogenase {ECO:0000313|EMBL:PAF53861.1};
GN ORFNames=BKH42_03775 {ECO:0000313|EMBL:PAF53861.1};
OS Helicobacter sp. 13S00482-2.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1476200 {ECO:0000313|EMBL:PAF53861.1, ECO:0000313|Proteomes:UP000216174};
RN [1] {ECO:0000313|EMBL:PAF53861.1, ECO:0000313|Proteomes:UP000216174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=13S00482-2 {ECO:0000313|EMBL:PAF53861.1,
RC ECO:0000313|Proteomes:UP000216174};
RX PubMed=28827684; DOI=10.1038/s41598-017-09091-7;
RA Gilbert M.J., Duim B., Timmerman A.J., Zomer A.L., Wagenaar J.A.;
RT "Whole genome-based phylogeny of reptile-associated Helicobacter indicates
RT independent niche adaptation followed by diversification in a
RT poikilothermic host.";
RL Sci. Rep. 7:8387-8387(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAF53861.1}.
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DR EMBL; MLAT01000005; PAF53861.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A268UC15; -.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000216174; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR009051; Helical_ferredxn.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR PANTHER; PTHR43100:SF2; FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE, CHLOROPLASTIC-LIKE; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 2.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 53..127
FT /note="NADH-ubiquinone oxidoreductase 51kDa subunit iron-
FT sulphur binding"
FT /evidence="ECO:0000259|Pfam:PF10589"
FT DOMAIN 145..224
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 242..548
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 642 AA; 71781 MW; 877597C4FDE5B026 CRC64;
MMQPFLPYSI GAGEFPNHLQ NEKMKSFIGW DGVVVFDENT DILDMLKNYA FQYQCYSEAC
GRCTPGKYGG RVLYDLLCRI QNDPDNLLEN INRLEETAHL MQNTSKCEIG KTTPKPILQM
LKTKREIFLN PQKASNTQKY ISKITAPCTD ACPSHVNIPA YIEGVRDMLF ADSLSATRSS
MPLAQVCGRV CPHPCESACR RSILDEPISI MELKRIGADY EFDMHLPYQH PKSITQHPCT
QKVAIIGAGP GGLSTAYYLA LEGVGVDVYE ALPVLGGEVA VGVPNYRMPI SNYNHDIDML
KELGVRFHTS SPMNEKSMLE LEKSHQAIVL ATGARISKKL GFSNEDPLLE GYLPAIKFMD
EVNLAQKFNL CEIPDIKGKN IVCVGGGFTS MDVVRSAIRL GAKSVTMLYR RDEATIIKNT
SKEEYHESVE EGVKFEFLST VVGVASKDNK ITAIDVGYFE LKKTPDSPKG ELIKIDKPPS
RFECDILIPA VSQIPDFSYL PKEWEIEITK WGTLQTQEGT FATSKKGVFG CGDCVSGPLT
IVNAVGQGKR VANVIKRYLK NNEISLSDEE KMEDYLHQIG VFNKSEDVRG WNKGLKRSES
QKVSPQERKK SFIEVNFGLS NQEAFYEAQR CMRCYYIAMA VL
//
